Results 101 to 110 of about 8,392,684 (386)

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

Advanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu   +37 more
wiley   +1 more source

Copyright and cultural work: an exploration [PDF]

, 2012
This article first discusses the contemporary debate on cultural “creativity” and the economy. Second, it considers the current state of UK copyright law and how it relates to cultural work.
Banks M., Beck U., Bustamante E., Caves R.E., Charlotte Waelde, Fairclough N., Florida R., Garnham N., Garnham N., Gill R., Hesmondhalgh D., Hesmondhalgh D., Howkins J., Komter A., Mattelart A., McGuigan J., Menger P.-M., Morris N., Negus K., O'Connor J., Oakley K. M., Philip Schlesinger, Rambach A., Schlesinger P., Schlesinger P., Schlesinger P., Standing G., Thussu D. K., Towse R., Waelde C.   +29 more
core   +1 more source

The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction

Advanced Science, EarlyView.
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang, Yuan Fang, Xiaoming Qin, Yiwei Zhang, Bo Kang, Li Zhong, Baoxin Liu, Jiachen Luo, Yidong Wei   +8 more
wiley   +1 more source

Ideology and cultural policy [PDF]

By examining voting behavior in a referendum on the construction of a concert hall in Germany, I show that political ideology influences cultural policy.
Niklas Potrafke
core  

Planning the cultural quarter in Birmingham's Eastside [PDF]

, 2007
Cultural planning and the development of cultural quarters has become a new orthodoxy in the revitalization of inner city industrial districts, yet this orthodoxy is now widely questioned as to whether it delivers on its promises.
Barber, A., Porter, E.
core   +1 more source

Suspended Tissue Open Microfluidic Patterning (STOMP)

Advanced Science, EarlyView.
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack, Lauren G. Brown, Alex J. Goldstein, Priti Mulimani, Jean Berthier, Asha R. Viswanathan, Irina Kopyeva, Jamison M. Whitten, Ariel Lin, Serena H. Nguyen, Thomas P. Leahy, Ella E. Bouker, Ruby M. Padgett, Natalie A. Mazzawi, Jodie C. Tokihiro, Ross C. Bretherton, Aaliyah Wu, Stephen J. Tapscott, Cole A. DeForest, Tracy E. Popowics, Erwin Berthier, Nathan J. Sniadecki, Ashleigh B. Theberge   +22 more
wiley   +1 more source

Cultural policy research in the real world: curating “impact”, facilitating “enlightenment”

, 2016
The very identity of cultural policy rests on a long-standing and widely accepted tension between “proper research” and policy advocacy, which has often resulted in resistance to the idea that robust, critical research can – or even should – be “useful ...
Eleonora Belfiore
semanticscholar   +1 more source

Digital Technology and Cultural Policy [PDF]

This paper reviews how digital technology, and the devices and broadband networks associated with it (the Internet, for short), can be expected to a ect the ways in which books, music, the visual arts, libraries and archived cultural heritage (cultural ...
Kieran Healy
core  

[Review of] Paul A. Scanlon, ed. Stories from Central and Southern Africa [PDF]

, 1987
Any work in the prestigious paperback African Writers Series commands immediate attention and respect. As policy makers and policy breakers wrestle about the South African question -- newly discovering the horrors of an inequality that has existed for ...
Jordan, W. A., III
core   +1 more source

DDX3 Regulates the Cap‐Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome

Advanced Science, EarlyView.
Japanese encephalitis virus (JEV) employs a cap‐independent (CI) translation strategy to evade host translational shutoff. During the shut‐off of host cellular canonical translation, DEAD‐box protein 3 (DDX3) bind to JEV UTRs to establish a closed‐loop architecture, and its interaction with poly(A)‐binding protein 1 (PABP1) to form DDX3/PABP1/eIF4G ...
Chenxi Li, Linjie Zhang, Chenyang Tang, Xuan Chen, Jing Shi, Qingyu Li, Xue Jiao, Jinyao Guo, Bin Wang, Kefan Bu, Abdul Wahaab, Yuguo Yuan, Ming‐an Sun, Yanhua Li   +13 more
wiley   +1 more source