Results 151 to 160 of about 8,996,586 (398)

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Culture Rules: The Foundations of the Rule of Law and Other Norms of Governance [PDF]

, 2003
This study presents evidence about relations between national culture and social institutions. We operationalize culture with data on cultural dimensions for over 50 nations adopted from cross-cultural psychology and generate testable hypotheses about ...
Goldschmidt, Chanan, Licht, Amir N., Schwartz, Shalom H.   +2 more
core  

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

A Comparative Analysis of Media Pluralism and Content Diversity Policy in Slovenia, Hungary, Croatia and Serbia [PDF]

In Medias Res, 2013
Vesna Ðukić, Sofija Drecun
doaj  

Integrative Cultural Policy

, 2010
Sangchin Chun
openalex   +1 more source

Bio-Determinants of Cultural Intelligence in DR Congo-Kinshasa and Need for its Related Policy within Organisations

, 2022
Christian L. Ayikwa
openalex   +2 more sources

Theatre production and cultural policy during the pandemic: Leadership and memory narratives [PDF]

, 2022
Milena Dragičević Šešić, Milena Stefanović   +1 more
openalex   +1 more source

Adjusting for cultural effects on countries’ education policy efficiency:an application of conditional full frontiers measures [PDF]

In this paper using Data Envelopment Analysis (DEA) we evaluate the influence of national culture on education policy efficiency for 20 OECD countries.
Halkos, George, Tzeremes, Nickolaos
core   +1 more source