Results 151 to 160 of about 3,202,546 (362)
How does one do a Practice-Based PhD in Filmmaking? [PDF]
This paper seeks to explore the issues raised by the process of engaging in a practice-based PhD in Filmmaking. As a sole practitioner the screenwriting doctoral student is able to explore her practice through the development of a screenplay, but what of
Anderson, L, Tobin, A
core
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Unveiling the Secrets of Pura Mangkunegaran’s Communication Practices: A Pathway to Cultural Preservation [PDF]
Basuki Agus Suparno +2 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
On the destiny of psychological practices, cultural contexts and the desemantisation trial
The paper presents an analysis of psychological practices, particularly group and family ones, seen in the context of the dynamics of the cultural situation emerging at the turn of the centuries.
Mikhaylova E.L.
doaj
Bilingual Education: A Reflective Practice Targeting Students' Cultural and Linguistic Capital
Valentina Cheptene
openalex +2 more sources
Ensuring "the development of the child ... to the maximum extent possible" is part of every child’s rights under the UN Convention on the Rights of the Child.
core
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source

