Results 171 to 180 of about 3,202,546 (362)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A Study of the Institutional Framework and Practices in Italian Cultural Heritage Conservation: Implications for China’s Cultural Heritage Protection [PDF]

Chengjun Jiang

openalex   +1 more source

Research on Practice Subjects Construction of Public Cultural Service in the Guangdong-Hong Kong-Macao Greater Bay Area

, 2022
Wei Wang
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Cultural Beliefs and Practices and Their Relationship with Food Consumption in Nigeria

, 2023
Joy‐Telu Hamilton‐Ekeke, Nedom Aga Segi   +1 more
openalex   +1 more source

Cultural Modifications in an Adolescent Earth-Oven Interment from Fiji: Sorting out Mortuary Practice [PDF]

, 2007
Cochrane, E, Douglas, M, Pietruesewsky, M, Reinke, S   +3 more
core   +1 more source

The Danish Cultural Heritage: Economics and Politics [PDF]

This paper deals with the Danish cultural heritage understood as the tangible heritage, mainly buildings. The paper briefly describes the political economy of conserving the cultural heritage and the means of preserving it. The main focus of the paper is,
Chr. Hjorth-Andersen
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Indigenous mental health research in the context of climate change: methodological reflections on language and barriers to cultural practice. [PDF]

BMJ Ment Health
Gougsa S, Pratt V, Kobei D, Kokunda S, Odochao S, Laiti J, George B, Sim J, Redvers N.   +8 more
europepmc   +1 more source

Nutritional Determinants, Cultural Practices, and Health Outcomes in Indian Postmenopausal Women: A Systematic Review

Senthamil Veni S, Nimeshika Devi S.V.L, Divya Jayachandran, E.Sathya Priya, Saravanasingh Karan Chand Mohan Singh, L.Sridevi, Chandrasekar R, T Susmitha, Kanniyakumari M, Renga Sundari, Ramamurthy Murugan   +10 more
openalex   +1 more source