Results 131 to 140 of about 2,176,785 (288)
Adventitious shoot propagation and cultural inputs in nursery production of a primocane-fruiting blackberry selection [PDF]
, 2006 Studies were conducted from January to October 2005 to determine the effect of root-cutting length on adventitious shoot yield and the management practices necessary to produce nurseryquality primocane-fruiting blackberry plants. The first portion of the
Clark, John R. +2 more
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
A Reflection on Teaching, Multiculturalism, and Access
ABO : Interactive Journal for Women in the Arts 1640-1830, 2012 Srividhya Swaminathan
doaj +1 more source
The Scope of Open Licenses in Cultural Contents Production and Distribution [PDF]
This paper aims to explore the impact of ex-ante legal status of creator on ex-post open license choice. It first describes the emergents Creative Commons licenses in Open Cultural Contents production and distribution.
Massimiliano Gambardella
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Why do creative industries cluster? An analysis of the determinants of clustering of creative industries [PDF]
Creative industries tend to concentrate mainly around large- and medium-sized cities, forming creative local production systems. The text analyses the forces behind clustering of creative industries to provide the first empirical explanation of the ...
Francesco Capone +2 more
core
Feminist Understanding of Productivity [PDF]
, 2002 The concept of productivity, meaning output per unit of input, is at once general and specific. Economists have used productivity as a very specific measure, denominated in dollars, which shows the output of a produced or consumed good per unit of ...
Perkins, Patricia E. (Ellie)
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source