Results 101 to 110 of about 830,162 (294)

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

open access: yesAdvanced Science, EarlyView.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao   +4 more
wiley   +1 more source

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

open access: yesAdvanced Science, EarlyView.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang   +8 more
wiley   +1 more source

Affective Aesthetics: Mapping Visual Cultural Memories in the 2022 Anti-Zero-COVID Policy Protest in China

open access: yesLateral
This article examines the meaning‐making work of historical, cultural, and visual references in the 2022 anti-Zero-COVID policy protests in China. Characterized by homemade protest placards, the wave of 2022 grassroots protests were striking, typically ...
Chelsea Wenzhu Xu
doaj   +1 more source

The Cultural Revolution

open access: yes, 1968
The Chinese Communist system was from its very inception based on an inherent contradiction and tension, and the Cultural Revolution is the latest and most violent manifestation of that contradiction. Built into the very structure of the system was an inner conflict between the desiderata, the imperatives, and the requirements that technocratic ...
Oksenberg, Michel   +4 more
openaire   +4 more sources

Thermally Degradable Biocompatible Hydrogel as Transient Encapsulation Coating for Implantable Sensors

open access: yesAdvanced Science, EarlyView.
A biocompatible hydrogel coating with tissue‐like mechanics and reversible dissolution triggered by a mild, physiologically compatible temperature drop (≈37°C → ≈25°C) was developed for the transient encapsulation of implantable devices. The physically crosslinked methylcellulose, polyethylene glycol and polyacrilic acid (MC/PEG/PAA) hydrogel ...
Francesca Persano   +14 more
wiley   +1 more source

FIFTY YEARS OF REGIONAL INEQUALITY IN CHINA: A JOURNEY THROUGH REVOLUTION, REFORM AND OPENNESS [PDF]

open access: yes
This paper constructs and analyses a long run time series for regional inequality in China from the Communist Revolution to the present. There have been three peaks of inequality in the last fifty years, coinciding with the Great Famine of the late 1950s,
Kanbur, Ravi, Zhang, Xiaobo
core   +1 more source

FREE CULTURE! Review of Michael Barr's work inspired by book on Cuban Cultural Policy [PDF]

open access: yes, 2016
This is a review of Michael Barr's work 'FREE CULTURE!' which was part of the exhibition 'RSA New Contemporaries' at the Royal Scottish Academy, Edinburgh (5-30 March 2016).
Brownrigg, Jenny
core  

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy   +16 more
wiley   +1 more source

IX. Early Modern Europe, 1500-1789

open access: yes, 1958
This chapter is concerned with the major political and economic developments which occurred in Western Civilization between about 1500 and the outbreak of the French Revolution in 1789.
Bloom, Robert L.   +6 more
core  

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu   +13 more
wiley   +1 more source

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