Results 121 to 130 of about 2,495,745 (312)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

ON THE CULTURE OF WRITING CULTURE FOR SERVICE DOCUMENTS

open access: yesVestnik Bishkek state university af K Karasaev
This study examined the writing standards for preparing official business documents. This study analyzes sources and examples related to document preparation, focusing on language norm compliance, the impact of linguistic errors on text perception, and document formatting requirements.
openaire   +1 more source

Evaluation of Services Our Way [PDF]

open access: yes, 2014
An evaluation of Services Our Way, a NSW Government service model designed to build the capacity of Aboriginal people to have greater access to mainstream and disability services and encourage self-directed support.
Karen R. Fisher   +4 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Problems and Potential for Canadian Child Welfare [PDF]

open access: yes, 2002
Canadian child welfare is not one single system, but more than 13 systems overseen by provincial and territorial governments and First Nations jurisdictions.
Callahan, M., Swift, K.
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Culture Counts: How Five Community-Based Organizations Serve Asian and Pacific Islander Youth [PDF]

open access: yes, 2003
This two-year effort to examine cultural competence involved an extensive literature review, a survey of organizations, and in-depth reviews of five community-based organizations: Asian American Recovery Services (Santa Clara office), East Bay Asian ...
Isami Arifuku   +3 more
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Cultural justice, ethics and practice: Summary of presentation [PDF]

open access: yes, 1993
The following cases and remarks are based on the author’s employment over six years in the Department of Social Welfare in Rotorua Specialist Services. The author discusses definitions that relate to the topic of cultural justice, ethics, and practice ...
Herbert, Averil May Lloyd
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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