The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Impact of educational interventions on the cultural competencies of nurses and students: a systematic review and meta-analysis. [PDF]
Toribio Martínez SJ +3 more
europepmc +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Global Cultural Change and Anxiety in Children and Adolescents: Analyzing Socialization Goals Over Three Decades in 70 Countries. [PDF]
Kulisch LK +3 more
europepmc +1 more source
Multimodal interaction enhancement of digital cultural heritage system: user behavior analysis and interface reconstruction of the heritage scanning library of the palace museum. [PDF]
Ke L, Qin H, Long J, Xiao P.
europepmc +1 more source
Applying the Stimulus - Organism - Response framework for exploring use intention - a case study for a digital cultural and creative product, The Forbidden City 365 app. [PDF]
Pan X, Zhong M.
europepmc +1 more source
The association between cultural connectedness and health-related quality of life among Indigenous peoples in the CANZUS countries: a systematic review. [PDF]
Brar S, Ben A, Ospina MB.
europepmc +1 more source
Reassessing Baumrind's framework: a systematic review of cultural adaptations and emerging parenting patterns in diverse societies. [PDF]
Widiastuti AA +3 more
europepmc +1 more source
The impact of cultural tourism experience on cultural identity: A case study of Mazu culture. [PDF]
Wang M, Lee HS, Chen WQ.
europepmc +1 more source

