Results 91 to 100 of about 2,178,912 (303)
Inside a cultural agency: team ethnography and knowledge exchange [PDF]
, 2015 This article undertakes an auto-critical analysis of the research team's ethnographic study of Cultural Enterprise Office (CEO), a Scottish creative business support agency.
Munro, Ealasaid +2 more
core +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Metadata Augmentation for Semantic- and Context- Based Retrieval of Digital Cultural Objects [PDF]
, 2007 Cultural objects are increasingly stored and generated in digital form, yet effective methods for their indexing and retrieval still remain an open area of research.
Pham, Binh, Smith, Robert
core +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Translational Turn in Visual Culture
REGAC - Revista de Estudios Globales y Arte Contempor�neo, 2019 Este volumen de REGAC se propone investigar la alianza teórica entre el arte visual y la traducción. El concepto de traducción visual se relaciona con una noción hermenéutica que reflexiona sobre las complejidades del artefacto artístico contemporáneo, pero también con un intento epistemológico de reflexionar entorno a los intercambios culturales y ...
openaire +5 more sources
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Forum: Qualitative Social Research, 2002 This intriguing, if somewhat difficult book, introduces the idea that we need methodologies to interpret the plethora of visual stimuli surrounding us. We can understand our culture through various visual representations.
Marilyn Lichtman
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