Results 31 to 40 of about 76,082 (262)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Analyzing the Upsurge of Violence and Mediation in the Nagorno-Karabakh Conflict
Stability : International Journal of Security and Development, 2014 This article aims to explore the mediation and upsurge of violence in the Nagorno-Karabakh conflict in order to introduce new elements into the mediation focused on the structure of violence.
Yoko Hirose, Grazvydas Jasutis
doaj +1 more source
School Violence and the Culture of Honor [PDF]
Psychological Science, 2009 We investigated the hypothesis that a sociocultural variable known as the culture of honor would be uniquely predictive of school-violence indicators. Controlling for demographic characteristics associated in previous studies with violent crime among adults, we found that high-school students in culture-of-honor states were significantly more likely ...
Ryan P. Brown +2 more
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The Examination of Cultural Peace Position in the Noble Quran [PDF]
آموزههای قرآنی, 2013 Contrary to the look of the contemporary criticizers, it seems that religions and holy texts could negate violence and have a crucial role to create peace. Specially, to access the opportunities which holy texts in this field have made before today’s men,
Mahdi Hasanzadeh, Rasoul Akbari Chaiichi
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Social Discrimination: Violence and Resistance of Female 19th Century in Jane Austen’s Persuasion
Journal of Language and Literaturehe 19th century in England, particularly during the Victorian era was defined by rigid social norms and power structures that placed women in subordinated roles.
Rezki Amelia Anggraeni +2 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Back to the future: primitivization, barbarization, or new scenarios of human development?
Russian Journal of Economics and LawObjective: to analyze the current digital stage of development from the viewpoint of the social structure and manifestations of an individual in it, as the latter has acquired a new form of identity – digital nomadism.
E. L. Iakovleva, R. A. Grigoryev
doaj +1 more source