Results 111 to 120 of about 10,768,025 (302)

Culture, institutions and democratization. [PDF]

, 2020
We construct a model of revolution and transition to democracy under individualistic and collectivist cultures. The main result is that, despite facing potentially more challenging collective action problems, countries with individualistic cultures are ...
Gorodnichenko, Yuriy, Roland, Gerard
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Obstacle crossing when dual-tasking in children with and without developmental coordination disorder

Scientific Reports
One of the essential motor skills in children’s lives is obstacle crossing. This ability is frequently employed in everyday scenarios, such as stepping over toys or miscellaneous objects on the floor. In a real-life context, the execution of this task is
Zdenek Svoboda, Lucia Bizovska, Tomas Klein, Ludvik Valtr, Kamila Banatova, Reza Abdollahipour, Peter Henry Wilson   +6 more
doaj   +1 more source

«Why do I have to continue?»: The problem of motor learning for students with disabilities in an electronic format

Фізична реабілітація та рекреаційно-оздоровчі технології
Purpose. The adaptability of the format of teaching people with disabilities is key to an effective educational process in the field of physical education and sport.
Andrii Yefremenko, Tetiana Sydorova, Viktoriia Horina, Serhii Kotliar, Roman Bondarenko   +4 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

J. G. Ballard and Making:An Experiment in Collaborative Practice [PDF]

, 2019
Ballard, Ballard, Ballard, Baxter, Bennett, Bigman, Bruffee, Coles, Ellegood, Knowles, Knowles, Luckhurst, Poggenpohl, Pringle, Robbins, Sato, Schneiderman, Steiner, William   +18 more
core   +1 more source

Commercial pond fish culture [PDF]

, 1987
Commercial pond fish culture practice is comparatively new in Nigeria. It is therefore very important that simple guidelines be provided for the establishment, development, and management of such projects.
Wokoma, S.A.
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Cloth & Culture Now [PDF]

, 2007
Cloth & Culture Now investigates the links between contemporary textile practice, strong traditional practice and overlapping global influences, offering a framework for the study of contemporary textile practice within a cultural specific, trans ...
Robins, Freddie
core