Results 141 to 150 of about 14,322,637 (389)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

THE IMPORTANCE OF UNIFORM CULTURE MEDIA IN THE BACTERIOLOGICAL EXAMINATION OF DISINFECTANTS [PDF]

, 1917
J. H. Wright
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Culture Shock

, 2013
Take one week living in our culture: Monday: A student quotes other students on Overheard at Gettysburg. “In the commons at 8:50am. Two girls. Completely serious. Girl 1: Have you been outside? Girl 2: Yea! It’s rape weather. Girl 1: I know. A girl could
Adamczak, Stephanie K., Frantz, Hannah M., Rupert, Elizabeth A.   +2 more
core  

Knowledge as Culture [PDF]

, 2012
Culture must not be seen as something that merely reflects an organization’s social reality: rather, it is an integral part of the process by which that reality is constructed.
Serrat, Olivier
core   +1 more source

Intercommunications of indexes of speed and power qualities of sportsmen single combat on the stage of the specialized base preparation

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2013
The purpose of work is a study of interdependence between indexes specially-preparatory and general preparatory exercises of sportsmen (boxing, sporting hand-to-hand fight hopak, fencing). 42 sportsmen took part in researches.
A.O. Nykytenko, S.A. Nikitenko, V.V. Busol, A.A. Nykytenko, M.R. Velychkovych, V.P. Martciv   +5 more
doaj  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Growth Rate and Generation Time of Bacteria, with Special Reference to Continuous Culture

, 1956
E. O. Powell
openalex   +1 more source

A FURTHER NOTE UPON THE EXPERIMENTAL PRODUCTION OF LEPROSY IN THE MONKEY (MACACUS RHESUS), WITH A CRITICAL STUDY OF THE CULTURE EMPLOYED [PDF]

, 1912
Charles W. Duval, Maurice Couret
openalex   +1 more source