Results 51 to 60 of about 3,343,725 (258)

Intimate and Personal Sphere in the System of Vital Values of the Anomalous Person – the Offender

Law and Safety, 2019
The study of the peculiarities of the structural and dynamic characteristics of the value and content sphere of the anomalous personality remains within the scope of actual psychological problems. The purpose of this study is to analyze the peculiarities
A. M. Bolshakova, T. O. Perevozna, I. O. Videnieiev, O. M. Khartsii   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Peculiarities of sensory motion reactions by students of KSAPC

Слобожанський науково-спортивний вісник, 2018
Purpose: to establish the features of the manifestation of sensorimotor reactions by students of various specializations of KSAPC. Material & Methods: analysis of scientific and methodological information, generalization of best practical experience ...
Yura Tropin, Vyacheslav Romanenko, Valeriy Goloha, Iryna Aleksieieva, Yana Aleksenko   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Integration of In Vitro Approaches With Whole-Genome Sequencing to Evaluate the Probiotic Potential of Lactic Acid Bacteria Isolated From Thit Chua: A Traditional Fermented Sour Meat in Northwest Vietnam

International Journal of Microbiology
Human demand for safe and high-quality fermented meat products has been increasing, emphasizing the need to develop innovative production approaches that incorporate functional starter cultures.
Nhung Thi Doan, Ha Viet Nguyen, Huy Duc Bui, Van Thi Nguyen, Linh Hai Nguyen Bui, Lan Anh Thi Hoang, Trung Thanh Trinh   +6 more
doaj   +1 more source

Characteristics of the level of the biogeometric profile of posture in women aged 41-45 with risk factors for cardiovascular diseases

Фізична реабілітація та рекреаційно-оздоровчі технології
Purpose. To assess the impact of the corrective and preventive program on the biogeometric profile of women aged 41-45 for the further development of the concept of physical culture and sports rehabilitation for women in the second period of mature age ...
Larysa Ruban, Victor Dzhym, Inna Torianyk, Olena Anosova, Marina Dzhym, Mykhailo Sanin   +5 more
doaj   +1 more source