Results 131 to 140 of about 8,891,769 (355)

Implementing Energy Efficiency & ESD from a Development Perspective [PDF]

, 2004
This note discusses the difficulties currently being experienced in implementing Ecological Sustainable Development (ESD) from a development perspective. It looks at what motivates developers and examines what is needed, either through mandatory measures
Hood, David A.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Analysis of the Application of Sundanese Batik in the Interior of the Grand Preanger Hotel [PDF]

, 2019
At first batik was known as a patterned cloth that contains a high philosophy which is one of Indonesian culture. The ability of batik to adapt to the times makes batik develop in terms of application.
Joshua, I. (Ivan ), Salayanti, S. (Santi )   +1 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Kültür Endüstrisine “Yedinci Kıta”dan Bakmak

Sakarya İletişim, 2023
Özünde kapitalist üretim ilişkilerini barındıran tüketim toplumlarında, kültür endüstrisi vasıtasıyla bireyler, sürekli olarak tüketime sevk edilmektedirler. Temelinde, özgürlükçü bir hava sergilemek yerine, zorlayıcı bir anlayış söz konusudur. Tek yönlü
Ömer Yavuz Özaslan, Gönül Cengiz
doaj  

An integrative study on the green cultural industry and its determinants in Jiangsu province, China under the cultural revitalization initiative: a global perspective

Frontiers in Psychology
IntroductionsThe cultural industry is pivotal in promoting sustainable economic development. This study aims to evaluate the economic efficiency of the cultural industry in Jiangsu Province by establishing a Data Envelopment Analysis (DEA) model and ...
Yaoyao Ding, Yaoyao Ding, Rong Zhang, Yuntao Zou, Yuntao Zou, Yuntao Zou   +5 more
doaj   +1 more source

The Critical Role of Art: Adorno between Utopia and Dystopia [PDF]

Kritike: An Online Journal of Philosophy, 2007
Reading or hearing about Theodor Adorno's ideas always results in quibbles. He strikes many as a naïve philosopher because of his reversal of concept and object; some see him as an anarchist because of his relentless critique of rationality; while to ...
Paolo A. Bolanos
doaj  

Consuming identity : the case of Scotland [PDF]

, 2001
The paper examines national identity in Scotland. The research explores how consumers perceive the symbols used to represent Scotland, how these symbols relate to their perceptions of contemporary Scottish identity and their responses to the use of these
Coombes, Emma, Hibbert, Sally, Hogg, Gillian, Varey, Richard   +3 more
core   +1 more source