Results 171 to 180 of about 8,418,026 (404)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

The Behavioral Equivalence of Organizational Culture [PDF]

open access: yes
Three decades of organizational cultural (OC) studies have seen change in both content and emphasis. This paper presents findings from an extensive review of literature on OC and highlights the relevance of OC with respect to individual, organizational ...
Rao Indu
core  

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

G. SİMMEL’DE SINIFSAL FARKLILIĞIN NESNELLEŞTİĞİ BİR ALAN: MODA FELSEFESİ

open access: yesFelsefe Dünyası, 2014
Düşünce tarihinde ilk kez Simmel “moda felsefesi” üzerine düşünerek“moda” fenomenini felsefi bir incelemenin konusu yapmıştır. Kendi içinde çokkatmanlı bir yapı barındıran moda, öncelikle sınıflı bir toplumun ürünüdür.
Emir G. Ülger
doaj  

CULTURAL CAPITAL, CULTURAL INDUSTRY AND INDUSTRIES CULTURE : CONCEPTUAL SEARCHES

open access: yesVestnik Tomskogo gosudarstvennogo universiteta. Kul'turologiya i iskusstvovedenie, 2020
openaire   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

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