Results 241 to 250 of about 6,992,473 (362)

Studies on the Synthetic Media or Culture of some Bacteria

, 1959
Hirotaka Nakanishi
openalex   +2 more sources

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Electromembrane Extraction Provides Unprecedented Selectivity for Drugs in Cell Culture Media Used in Organoid and Organ-on-Chip Systems. [PDF]

Anal Chem
Kogler S, Skottvoll FYS, Hrušková H, Rise F, Aizenshtadt A, Krauss S, Ro Berg-Larsen H, Hansen FA, Wilson SR.   +8 more
europepmc   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

FEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Regeneration of Spent Culture Media for Sustainable and Continuous mAb Production via Ion Concentration Polarization. [PDF]

Biotechnol Bioeng
Wynne E, Yoon J, Park D, Cui M, Morris C, Lee J, Wang Z, Yoon S, Han J.   +8 more
europepmc   +1 more source

Spontaneous decomposition of glutamine in cell culture media

, 1962
George L. Tritsch, Ginny Moore
openalex   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

NMR metabolomics of plant and yeast-based hydrolysates for cell culture media applications - A comprehensive assessment. [PDF]

Curr Res Food Sci
Combe M, Isaac KS, Potter G, Sokolenko S.   +3 more
europepmc   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Predictive value of homocysteine levels in embryo culture media for embryo selection in infertile patients with endometriosis. [PDF]

Turk J Obstet Gynecol
İmamoğlu M, Öncül M, Tüten A, Şentürk LM.   +3 more
europepmc   +1 more source