Results 241 to 250 of about 3,626,823 (307)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Editorial: Superheroes and villains: engagement, effects, and empowerment

open access: yesFrontiers in Psychology
Julia Kneer   +2 more
doaj   +1 more source

Non-Invasive Preimplantation Genetic Testing: Cell-Free DNA Detection in Embryo Culture Media Using a Plasmonic Biosensor. [PDF]

open access: yesAnal Chem
Bellassai N   +8 more
europepmc   +1 more source

Deep Learning-Powered Colloidal Digital SERS for Precise Monitoring of Cell Culture Media. [PDF]

open access: yesNano Lett
Zheng P   +6 more
europepmc   +1 more source

Microfluidic droplets with amended culture media cultivate a greater diversity of soil microorganisms. [PDF]

open access: yesAppl Environ Microbiol
Dai J   +14 more
europepmc   +1 more source

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