Results 41 to 50 of about 22,966,310 (260)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Pedagogical Uses of Digital Technologies by Pre and In-Service Teachers: Literature Review from a Global Perspective to the Chilean Context

Proceedings, 2018
The broad integration of information and communication technologies (ICT) in students’ and teachers’ lives requires education professionals to think of new ways to provide teaching and learning opportunities.
Angela Novoa-Echaurren, Alejandra Canales-Tapia   +1 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Visual archives towards the recovery and reactivation of artistic and pedagogical heritage at the School of Fine Arts in Porto

Fotocinema: Revista Científica de Cine y Fotografía, 2022
This article reviews the development of a visual archive within the scope of a funded project Wisdom Transfer that was realised at the Faculty of Fine Arts (FBAUP), University of Porto, in Portugal from 2018 to 2021.
Cláudia Lima, Susana Barreto, Eliana Penedos-Santiago   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Digital storytelling in sex education. Avoiding the pitfalls of building a ‘haram’ website

Seminar.net, 2010
This article discusses a participant design research project. The project aimed to provide information about sex and sexuality to groups considered to be vulnerable due to lack of knowledge and cultural barriers.
Pauline Borghuis, Christa de Graaf, Joke Hermes   +2 more
doaj  

The exercise world of otaku: extended body techniques, alternative body projects, and controllable social architecture

The Journal of Chinese Sociology
Why do some people opt for exergames like Ring Fit Adventure (RFA) over traditional exercise venues such as gyms? Focusing on the case of RFA, this study examines the social factors that contribute to this preference and explores the potential of video ...
Jiangwei Zhou, Yu Zhao
doaj   +1 more source

The Survival of the Dukuh Indigenous Community Amidst the Modern Crisis: Paradoxical Aesthetics as a Form of Cultural Resilience

Mudra: Jurnal Seni Budaya
This research explores the cultural resilience of the Dukuh Indigenous Community in Garut during modern crises, focusing on the philosophical values of weweling (ancestral advice) written in Pegon script.
Iip Sarip Hidayana, Sophia Septiani, Rufus Goang Swaradesy   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source