Results 121 to 130 of about 7,210,484 (302)
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Promotive factors for callus initiation and plant regeneration in upland rice
Factors promotive to the initiation of embryogenic callus and regeneration of plants in upland rice were investigated using mature dehulled seeds. The objectives are to enhance the production of embryrogenic callus and increase regeneration of plants ...
Marilyn M. Belarmino
doaj
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Market orientation development in family owned small and medium enterprises [PDF]
This research examined the nature of Market Orientation and analysed the extent of Market Orientation development in family owned small and medium sized enterprises.
Lawrence, A
core
Cattleya mendelii es una orquídea endémica de Colombia de gran valor ornamental que se encuentra en peligro de extinción a causa de la recolección masiva y a la destrucción de sus hábitats naturales por la acción antrópica.
Seir Antonio Salazar-Mercado
doaj
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
The impact of organisational culture on WiMax adoption by Saudi SMEs [PDF]
Although there is some research that examines Worldwide Inter-operability for Microwave Access (WiMax) adoption, the role of the organisational culture by Small and Medium Enterprises (SMEs) has not been studied in the context of the Kingdom of Saudi ...
Abousaber, I, Papazafeiropoulou, A
core
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Novel media, coconut bile salt medium for aflaltoxigenic mold detection
Aflatoxins are potent carcinogen contaminated in food. The toxins produce by Aspergillus flavus and Aspergillus parasiticus. Both of these molds habitually isolated in environment and agriculture stuff in Thailand.
Bordin Butr-Indr
doaj

