Results 121 to 130 of about 7,210,484 (302)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Promotive factors for callus initiation and plant regeneration in upland rice

open access: yesAnnals of Tropical Research, 2002
Factors promotive to the initiation of embryogenic callus and regeneration of plants in upland rice were investigated using mature dehulled seeds. The objectives are to enhance the production of embryrogenic callus and increase regeneration of plants ...
Marilyn M. Belarmino
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Market orientation development in family owned small and medium enterprises [PDF]

open access: yes, 2011
This research examined the nature of Market Orientation and analysed the extent of Market Orientation development in family owned small and medium sized enterprises.
Lawrence, A
core  

Germinación asimbiótica de semillas y desarrollo in vitro de plántulas de Cattleya mendelii Dombrain (Orchidaceae) Asymbiotic seed germination and in vitro seedling development of Cattleya mendelii Dombrain (Orchidaceae)

open access: yesActa Agronómica, 2012
Cattleya mendelii es una orquídea endémica de Colombia de gran valor ornamental que se encuentra en peligro de extinción a causa de la recolección masiva y a la destrucción de sus hábitats naturales por la acción antrópica.
Seir Antonio Salazar-Mercado
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The impact of organisational culture on WiMax adoption by Saudi SMEs [PDF]

open access: yes, 2011
Although there is some research that examines Worldwide Inter-operability for Microwave Access (WiMax) adoption, the role of the organisational culture by Small and Medium Enterprises (SMEs) has not been studied in the context of the Kingdom of Saudi ...
Abousaber, I, Papazafeiropoulou, A
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Novel media, coconut bile salt medium for aflaltoxigenic mold detection

open access: yesJournal of Associated Medical Sciences, 2012
Aflatoxins are potent carcinogen contaminated in food. The toxins produce by Aspergillus flavus and Aspergillus parasiticus. Both of these molds habitually isolated in environment and agriculture stuff in Thailand.
Bordin Butr-Indr
doaj  

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