Results 1 to 10 of about 6,361 (264)

Laser-assisted microbial culturomics [PDF]

Nature Communications
Even though metagenomics have revolutionized the characterization of the human microbiome, detailed mechanistic studies are impracticable, as there is a dearth of robust culture collections.
Taoran Qu, Lothar Koch, Rumjhum Mukherjee, Yilin Tu, Amy L. Seidel, Lisan D. Püttmann, Andreas Winkel, Ines Yang, Jasmin Grischke, Dejia Liu, Willem F. Wolkers, Sophie Kittler, Boris Chichkov, Meike Stiesch, Szymon P. Szafrański   +14 more
doaj   +4 more sources

From Culturomics to Clinical Microbiology and Forward [PDF]

Emerging Infectious Diseases, 2018
Culturomics has permitted discovery of hundreds of new bacterial species isolated from the human microbiome. Profiles generated by using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry have been added to the mass ...
Grégory Dubourg, Sophie Baron, Frédéric Cadoret, Carine Couderc, Pierre-Edouard Fournier, Jean-Christophe Lagier, Didier Raoult   +6 more
doaj   +5 more sources

Coupling culturomics and metagenomics sequencing to characterize the gut microbiome of patients with cancer treated with immune checkpoint inhibitors [PDF]

Gut Pathogens
Background The gut microbiome represents a novel biomarker for melanoma and non-small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICI).
Khoudia Diop, Babacar Mbaye, Somayeh Nili, Alysé Filin, Myriam Benlaifaoui, Julie Malo, Anne Sophie Renaud, Wiam Belkaid, Sebastian Hunter, Meriem Messaoudene, Karla A. Lee, Arielle Elkrief, Bertrand Routy   +12 more
doaj   +3 more sources

Thomasclavelia ramosa and alcohol-related hepatocellular carcinoma: a microbial culturomics study [PDF]

Gut Pathogens
Background Gut microbiota alteration is implicated in the pathogenesis of alcoholic liver disease (ALD) and associated hepatocellular carcinoma (HCC). No study has characterized the dysbiosis associated with ALD by microbial culturomics, which certifies ...
Reham Magdy Wasfy, Anissa Abdoulaye, Patrick Borentain, Babacar Mbaye, Maryam Tidjani Alou, Aurelia Caputo, Claudia Andrieu, Giovanna Mottola, Anthony Levasseur, Matthieu Million, Rene Gerolami   +10 more
doaj   +3 more sources

A streamlined culturomics case study for the human gut microbiota research [PDF]

Scientific Reports
Bacterial culturomics is a set of techniques to isolate and identify live bacteria from complex microbial ecosystems. Despite its potential to revolutionize microbiome research, bacterial culturomics has significant challenges when applied to human gut ...
Hyunjoon Park, Soyoung Yeo, Chang Beom Ryu, Chul Sung Huh   +3 more
doaj   +3 more sources

Integrating metagenomics and culturomics to uncover the soil bacterial community in Asparagus cochinchinensis cultivation. [PDF]

Front Microbiol
Asparagus cochinchinensis is a medicinal plant in China, which has gained attention owing its protective effect in human health. However, there are seldom studies to systematically reveal the rhizosphere bacterial community of A. cochinchinensis. In this
Yu J, Yang S, Zhang X, Liu X, Tang X, Wang L, Chen J, Luo H, Liu C, Song C.   +9 more
europepmc   +4 more sources

An optimized culturomics strategy for isolation of human milk microbiota [PDF]

Frontiers in Microbiology
Viable microorganisms and a diverse microbial ecosystem found in human milk play a crucial role in promoting healthy immune system and shaping the microbial community in the infant’s gut.
Fan Wang, Lingmin Yu, Yuting Ren, Qianwen Zhang, Shanshan He, Minlei Zhao, Zhili He, Qi Gao, Jianguo Chen   +8 more
doaj   +3 more sources

Editorial Note: Extensive culturomics of 8 healthy samples enhances metagenomics efficiency. [PDF]

PLoS One
PLOS One Editors.
europepmc   +4 more sources

Culturomics of the pig tonsil microbiome identifies new species and an untapped source of novel antimicrobials. [PDF]

Microbiome
In humans and pigs, altered composition of the microbiota associated with the epithelium of the palatine tonsils has been associated with bacterial or viral infection and lymphoid tissue inflammation.
de Oliveira IMF, Fredriksen S, Gutiérrez MF, Harmsen HJM, Boekhorst J, van Baarlen P, Wells JM.   +6 more
europepmc   +4 more sources

High-throughput microbial culturomics using automation and machine learning [PDF]

Nature Biotechnology, 2023
Pure bacterial cultures remain essential for detailed experimental and mechanistic studies in microbiome research, and traditional methods to isolate individual bacteria from complex microbial ecosystems are labor-intensive, difficult-to-scale and lack ...
Yiming Huang, Ravi U. Sheth, Shijie Zhao, Lucas Cohen, Kendall Dabaghi, Thomas U. Moody, Yiwei Sun, Deirdre Ricaurte, Miles Richardson, Florencia Velez-Cortes, Tomasz Blazejewski, A. Kaufman, Carlotta Ronda, Harris H. Wang   +13 more
semanticscholar   +2 more sources