Results 121 to 130 of about 233,302 (259)

Disease Activity and Cumulative Damage as Treatment Targets for Chronic Obstructive Pulmonary Disease. [PDF]

Tuberc Respir Dis (Seoul)
Oh YM.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Analysis of the macroseismic cumulative damage in the seismic sequences in Italy. [PDF]

Bull Earthq Eng
Vannucci G.
europepmc   +1 more source

A New Model to Study Fatigue in Dental Implants Based on Probabilistic Finite Elements and Cumulative Damage Model. [PDF]

Appl Bionics Biomech, 2017
Prados-Privado M, Bea JA, Rojo R, Gehrke SA, Calvo-Guirado JL, Prados-Frutos JC.   +5 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Cumulative damage characteristics of tunnel initial support concrete under blasting load. [PDF]

Sci Rep
Zhao Y, Zhang Z, Ge L, Xu L, Zhao H, Yu M.   +5 more
europepmc   +1 more source

Ductility and strength reduction factors for degrading structures considering cumulative damage. [PDF]

ScientificWorldJournal, 2014
Bojórquez E, Ruiz SE, Reyes-Salazar A, Bojórquez J.   +3 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Simulation Experimental Study on Evolution Law of Cumulative Damage in Coal under Shocks by Multiple High Pressure Air Blasting. [PDF]

ACS Omega
Yan S, Gao F, Sun B, Du Z, Liu Q, Ji N, Ye H.   +6 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source