Results 201 to 210 of about 7,742,545 (234)

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Cumulative live birth rates in in-vitro fertilization

Minerva Ginecologica, 2019
Traditionally, in-vitro fertilization (IVF) success rates have been reported in terms of live birth per fresh cycle or embryo transfer. However, reporting IVF outcomes using cumulative live birth rates (LBR), defined as the first live birth following the use of all fresh and frozen embryos derived from a single ovarian stimulation cycle appears to be a
Drakopoulos, Panagiotis, Errázuriz, Joaquín, Santos-Ribeiro, Samuel, Tournaye, Herman, Vaiarelli, Alberto, Pluchino, Nicola, Blockeel, Christophe, Polyzos, Nikolaos P   +7 more
openaire   +5 more sources

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Cumulative live birth rates after IVF in patients with polycystic ovaries: phenotype matters

Reproductive BioMedicine Online, 2018
Do cumulative live birth rates (CLBR) vary among women with different polycystic ovary syndrome (PCOS) phenotypes who undergo IVF/intracytoplasmic sperm injection (ICSI) treatment?In this retrospective cohort study, data from 567 patients undergoing an assisted reproductive technology (ART) cycle between January 2010 and December 2015 were collected ...
Michel De Vos, Nikolaos Polyzos, MIGUEL Raimundo   +2 more
exaly   +4 more sources

Total blastocyst usable rate is a predictor of cumulative live birth rate in IVF cycles

Journal of Gynecology Obstetrics and Human Reproduction
Despite advances in IVF techniques, determining the prognostic factors influencing cumulative live birth rate (CLBR) remains crucial for optimizing outcomes. Among the various key performance indicators in the lab, blastulation rate, and more specifically Total Blastocyst Usable Rate (TBUR), has gained particular interest.
Chaillot, M., Reignier, A., Fréour, T.
openaire   +5 more sources

Does PGT-A affect cumulative live birth rate?

Current Opinion in Obstetrics & Gynecology, 2023
Purpose of review Preimplantation genetic testing for the purpose of aneuploidy screening (PGT-A) has increased in use over the last decade. Recent findings Whether PGT-A benefits all of the patients that choose to employ it has been a concern, as recent studies have highlighted a ...
Serin, Seckin, Eric J, Forman
openaire   +2 more sources

Estradiol on trigger day: Irrelevant to live birth rates of fresh cycles but positively associated with cumulative live birth rates

International Journal of Gynecology & Obstetrics, 2023
AbstractObjectiveTo assess the effects of estradiol (E2) on trigger day on cumulative live birth rates (CLBRs), and pregnancy outcomes after fresh and frozen–thawed embryo transfer (FET).MethodsThis multicenter retrospective cohort study included 42 315 patients from five reproductive centers. Six subgroups were divided according to E2 on trigger day (&
Meng Wang, Lei Jin, Juanzi Shi, Yundong Mao, Cuilian Zhang, Rui Huang, Xiaoyan Liang   +6 more
openaire   +2 more sources

Association between the number of oocytes and cumulative live birth rate: A systematic review

Best Practice & Research Clinical Obstetrics & Gynaecology, 2023
The available literature is controversial regarding the association between the number of oocytes retrieved and the cumulative live birth rate (CLBR). Although some authors report a continuous increase in the CLBR with the number of oocytes retrieved, others have found a plateau.
Neves, Ana Raquel, Montoya Botero, Pedro, Guedj, Noémie, Polyzos, Nikolaos P   +3 more
openaire   +3 more sources

Number needed to freeze: cumulative live birth rate after fertility preservation in women with endometriosis [PDF]

Reproductive BioMedicine Online, 2021
Research question: How does the number of oocytes used affect the cumulative live birth rate in endometriosis patients who had their oocytes vitrified for fertility preservation (FP)?
Antonio Pellicer, Juan García-Velasco, Maria JOSÉ De Los Santos   +2 more
exaly   +1 more source

Cumulative live-birth rates after assisted reproductive technology

Current Opinion in Obstetrics & Gynecology, 2010
Despite the promising success rates of IVF, many couples have to undergo several cycles before achieving live birth. In counseling patients faced with subfertility, it is important to provide cumulative live-birth rates. This review evaluates the current knowledge on cumulative rates, summarizing recently published evidence.Existing data have been ...
Vasiliki A, Moragianni, Alan S, Penzias
openaire   +2 more sources