0289 ”david´s cheese bread” method: workload quantitative exposure thresholds detection using adjusted hazard multivariate parametric modelling, useful in cumulative-trauma disorders prevention and within their causal assessment [PDF]
, 2017 David Alvarez Rincón +1 more
openalex +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Advanced Biology, EarlyView.Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams +7 more
wiley +1 more source
Changing Course: Improving Outcomes for African-American Males Involved With Child Welfare Systems [PDF]
, 2014 This paper draws attention to African-American boys and young men who are involved with the nation's child welfare systems and identifies policies and practices that can help to improve their experiences and ...
Frank Farrow +3 more
core
Advanced Biology, EarlyView.The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna +6 more
wiley +1 more source
Influence of Multiple Traumatic Event Types on Mental Health Outcomes: Does Count Matter? [PDF]
, 2018 The experience of potentially traumatizing events (PTEs) may be associated with conflicting outcomes: individuals may experience greater psychological distress (dose-response theory), or individuals may become more resilient against repeated PTEs (stress-
Brown, Lily A +5 more
core +1 more source
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Advanced Biology, EarlyView.Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
Ergonomics in the Workplace: Is It Time for an OSHA Standard? [PDF]
, 2001 Improper ergonomic design of jobs is one of the leading causes of work-related illness, accounting for perhaps a third of employers’ costs under state workers’ compensation laws.
Rappaport, Edward
core +5 more sources
Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
Advanced Functional Materials, EarlyView.After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen +9 more
wiley +1 more source