Results 231 to 240 of about 166,028 (379)

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Cumulative Violence and Post-Traumatic Stress: An Integrative Model of Coping and Resilience Among Women Exposed to Sexual and Conflict-Related Violence. [PDF]

Eur J Investig Health Psychol Educ
Bar N, Shapira S, Braun-Lewensohn O.
europepmc   +1 more source

Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction

Advanced Science, EarlyView.
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod, Ryan N. Stack, Sarah E. Kubik, Stephanie A. Huang, Chloe P. Whitworth, Wen Y. Aw, Elizabeth L. Doherty, Sara M. Meehan, Prabir Roy‐Chaudhury, William J. Polacheck   +9 more
wiley   +1 more source

Climate trauma from wildfire exposure impacts cognitive decision-making. [PDF]

Sci Rep
Nan J, Jaiswal S, Ramanathan D, Withers MC, Mishra J.   +4 more
europepmc   +1 more source

Detection of early symptoms of cumulative trauma disorders among mothers of handicapped children: a pilot study

, 2018
Gülşah Kınalı, Ferda Dokuztuğ Üçsular   +1 more
openalex   +2 more sources

In Situ Proliferating Peptide Nanoparticle Augments Multi‐Target Intervention of Secondary Brain Damage Following Subarachnoid Hemorrhage

Advanced Science, EarlyView.
This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang, Peisen Yao, Fuxiang Chen, Shufa Zheng, Xuegang Niu, Haojie Wang, Yuanxiang Lin, Bin Gao, Dezhi Kang   +8 more
wiley   +1 more source

Association of childhood maltreatment and adverse lifetime experiences with post-injury psychopathology: evidence from the China Severe Trauma Cohort. [PDF]

BMC Med
Wen S, Zeng Y, Xu Y, Xu S, Chen W, Wang G, Zhang W, Song H.   +7 more
europepmc   +1 more source

Hair cortisol concentrations are associated with hippocampal subregional volumes in children

, 2020
Bender, A., Bögl, K., Heim, C., Keresztes, A., Raffington, L., Shing, Y.   +5 more
core   +1 more source

Comparative Analysis of Clinical Outcomes and Financial Aspects of Phototherapies and Immunotherapy for Cancer

Advanced Science, EarlyView.
This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan, Kun Shao, Roopa Hebbandi Nanjundappa, Daniel‐Jiajun Yu, Marianne Stanford, Huile Gao, Channakeshava Sokke Umeshappa   +6 more
wiley   +1 more source

The relationship between childhood trauma, rs1360780 genotypes, <i>FKBP5</i> intron 7 methylation and posttraumatic stress disorder in women who have experienced rape. [PDF]

Eur J Psychotraumatol
Nöthling J, Womersley JS, Mhlongo S, Lombard C, Abrahams N, Seedat S, Hemmings SMJ.   +6 more
europepmc   +1 more source