Results 251 to 260 of about 172,786 (377)

Ergonomic basket design to reduce cumulative trauma disorders in tea leaf plucking operation

, 2012
Nihar Bhattacharyya, Debkumar Chakrabarti   +1 more
openalex   +2 more sources

Superando la teta asustada: Structural violence, intergenerational trauma, and indigenous Peruvian women’s agency [PDF]

, 2010
Espinoza, Damarys
core   +1 more source

Time‐Dependent Therapeutic Effect of S‐Ketamine on PTSD Mediated by VTA‐OFC Dopaminergic Neurocircuit

Advanced Science, EarlyView.
This study reveals that early rather than late administration of S‐ketamine can ameliorate PTSD symptoms. This phenomenon is attributed to reversing the progressive inhibition of VTADA neurons and the function of VTADA‐OFC circuit following stress. Targeted stimulation of the OFC by TI‐NIBS to enhance DA release effectively extends the therapeutic time
Ye Wang, Lei Liu, Jinghao Wang, Jiannan Li, Huiming Li, Rui Wang, Hui Wang, Min Wang, Quanying Liu, Zhongmin Fan, Yunyun Zhang, Xinxin Zhang, Dan Wang, Sa Wang, Rou Xue, Jindong Mao, Min Cai, Pengfei Wei, Hailong Dong, Yumei Wu, Guangchao Zhao   +20 more
wiley   +1 more source

The mediating roles of stressful life events and negative affect in the relationship between childhood maltreatment and non-suicidal self-injury among clinical adolescents. [PDF]

Eur J Psychotraumatol
He J, Chen Z, Shen Y, Tian Y, Li Y, Ou J.   +5 more
europepmc   +1 more source

Determining Risk Factors in Cumulative Trauma Disorders of Computer Users and Effects of Risk Factors on Disability

, 2015
Özgül Bozkurt Tuncer, Hakan Genç, Barış Nacir, Hatice Rana Erdem   +3 more
openalex   +1 more source

Oral Celastrol Micelles Forming High‐Density Lipoprotein Corona Targeting Hepatocytes for MASLD Treatment

Advanced Science, EarlyView.
Upon oral administration, OPDEA‐PCL/CEL micelles passed through the stomach acid intact, then quickly penetrated the intestinal mucus and transported into circulation, where they captured HDL to form a protein corona and target hepatocyte SR‐B1 receptors, inducing endocytosis.
Chang Xu, Haoru Zhu, Kai Wang, Haitao Hu, Xuyong Wei, Dongdong Xu, Jing Zhang, Yanpeng Liu, Jun Chen, Youqing Shen, Nasha Qiu, Xiao Xu   +11 more
wiley   +1 more source

The relationship between lifetime trauma exposure and psychosis in a multi-country case-control study in Africa. [PDF]

SSM Ment Health
Stevenson A, Misra S, Girma E, Akena D, Alemayehu M, Ametaj AA, Gelaye B, Gichuru S, Kariuki SM, Koenen KC, Kwobah EK, Kyebuzibwa J, Mwema RM, Newman CP, Newton CRJC, Ongeri L, Pretorius A, Sharma M, Stein DJ, Stroud RE, Teferra S, Zingela Z, Atwoli L.   +22 more
europepmc   +1 more source

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

Advanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li, Ping Deng, Tengfei Fan, Yuchen Qu, Miduo Tan, Yidan Liang, Peng Gao, Yongchun Peng, Mingke Qin, Sheng Jie, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Rui Tian, Min Li, Zhengping Yu, Zhou Zhou, Huifeng Pi   +24 more
wiley   +1 more source

Cumulative exposure to childhood adversity and risk of adult psychosis: a dose-response meta-analysis. [PDF]

Psychol Med
Flinn A, Hefferman-Clarke R, Parker S, Allsopp K, Zhou L, Begemann M, Bentall R, Varese F.   +7 more
europepmc   +1 more source

Sleep Deprivation Aggravates Periodontitis Through Trigeminal‐Periodontal Neuroimmune Pathway Mediated by the AChE‐ACh‐α7nAChR Axis

Advanced Science, EarlyView.
Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu, Qi Huang, Mingcong Yang, Ziyu Huang, Kamoran Tuerhong, Yue Zu, Ying Xie, Xuehui Hu, Qianyu Zhang, Ping He, Nannan Huang, Rong Zhang, Yuzhou Li, Sheng Yang   +13 more
wiley   +1 more source