This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao +13 more
wiley +1 more source
Extreme weather and climate-related adverse childhood experiences are a humanitarian crisis during the 21st century. [PDF]
Thapa S, Giri S, Ross AG.
europepmc +1 more source
A closed‐loop bioelectronic artificial pancreas patch is presented for glucose monitoring and regulation. Utilizing transiently dissolvable microneedle arrays integrated with microtube arrays, the patch efficiently delivers insulin into interstitial fluid, eliminating the need for external long needles. In diabetic pigs, it demonstrates excellent blood
Yiqun Liu +9 more
wiley +1 more source
Barriers and facilitators to treatment in severe and enduring eating disorders: a mixed-methods study of access, engagement, and lived experience. [PDF]
Lubieniecki G, McGrath I, Sharp G.
europepmc +1 more source
Post-Concussion Syndrome and Functional Neurological Disorder: Diagnostic Interfaces, Risk Mechanisms, and the Functional Overlay Model. [PDF]
Mavroudis I +5 more
europepmc +1 more source
Prevalence and correlates of anxiety, depression, and symptoms of trauma among Palestinian adults in Gaza after a year of war: a cross-sectional study. [PDF]
Zughbur MR +8 more
europepmc +1 more source
Endocannabinoid and N-acylethanolamine concentrations in hair of female patients with posttraumatic stress disorder - associations with clinical symptoms and outcomes following multimodal trauma-focused inpatient treatment. [PDF]
Bergunde L +8 more
europepmc +1 more source
The effect of childhood trauma on bipolar depression. [PDF]
Guillen-Burgos HF +7 more
europepmc +1 more source
Interacting immediate and long-term action regulation in suicidal behavior. [PDF]
Murphy N +13 more
europepmc +1 more source

