Results 61 to 70 of about 175,479 (337)

Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants

Epigenetics, 2023
Pregnancy can exacerbate or prompt the onset of stress-related disorders, such as post-traumatic stress disorder (PTSD). PTSD is associated with heightened stress responsivity and emotional dysregulation, as well as increased risk of chronic disorders ...
Seyma Katrinli, Alicia K Smith, Stacy S. Drury, Jonathan Covault, Julian D. Ford, Vijender Singh, Bo Reese, Amy Johnson, Victoria Scranton, Pamela Fall, Margaret Briggs-Gowan, Damion J Grasso   +11 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Who can best support us through cumulative trauma exposure in the media?

Acta Psychologica
In the digital age, exposure to media-related trauma is increasing, triggering clinical symptoms, including post-traumatic stress disorder (PTSD), even in those without direct trauma exposure.
Shir Porat-Butman, Sarit Agam, Shiran Glazer, Eden Hakimi-Pour, Hanna Levenberg, Zohar Nimni, Maya Nissenhaus-Apel, Selin Simrooglu, Yael Shahar, Ariel Reuveni, Nof Vaknin, Einat Levy-Gigi   +11 more
doaj   +1 more source

Youth Incarceration, Health, and Length of Stay [PDF]

, 2017
For youth from marginalized communities, the pathway into the juvenile justice system occurs against a backdrop of disproportionately high levels of stress, complex trauma, and adverse childhood experiences.
González, Thalia
core   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

LER - lesão por esforços repetitivos: um conceito falho e prejudicial RSI - Repetitive Strain Injury: a questionable and harmful concept

Arquivos de Neuro-Psiquiatria, 1999
O conceito de que movimentos repetitivos ou posturas prolongadas causam lesões não tem suporte científico. Os sintomas dolorosos e sensitivos apresentados pelos pacientes são melhor explicados como um fenômeno psicológico e psicossocial, como ...
JOSÉ TEOTONIO DE OLIVEIRA
doaj   +1 more source

Maintenance of aversive memories shown by fear extinction-impaired phenotypes is associated with increased activity in the amygdaloid-prefrontal circuit [PDF]

, 2016
Although aversive memory has been mainly addressed by analysing the changes occurring in average populations, the study of neuronal mechanisms of outliers allows understanding the involvement of individual differences in fear conditioning and extinction.
Caioli, Silvia, De Bartolo, Paola, LARICCHIUTA, DANIELA, PETROSINI, Laura, Saba, Luana, Zona, Cristina   +5 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Adverse childhood experiences, mental illness, HIV and offending among female inmates in Durban, South Africa

South African Journal of Psychiatry
Background: Childhood adversities and adult trauma are common among female inmates. Associations have been documented with childhood adversities and mental illness, personality disorders, human immunodeficiency virus (HIV) and violent offending. However,
Samantha Naidoo, Saeeda Paruk, Liezel Ferreira, Ugasvaree Subramaney   +3 more
doaj   +1 more source

Subjective quality of life in war-affected populations [PDF]

, 2013
PMCID: PMC3716711This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided
Ajdukovic, D, Bogic, M, Franciskovic, T, Galeazzi, GM, Giacco, D, Kucukalic, A, Lecic-Tosevski, D, Matanov, A, Morina, N, Popovski, M, Priebe, S, Schuetzwohl, M   +11 more
core   +3 more sources