Results 71 to 80 of about 82,554 (326)

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

open access: yesAdvanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang   +6 more
wiley   +1 more source

Elastic Shape Analysis of Brain Structures for Predictive Modeling of PTSD [PDF]

open access: yesarXiv, 2021
There is increasing evidence on the importance of brain morphology in predicting and classifying mental disorders. However, the vast majority of current shape approaches rely heavily on vertex-wise analysis that may not successfully capture complexities of subcortical structures.
arxiv  

Prevalence of Posttraumatic Stress Disorder and Depression Among Internally Displaced Persons in Mogadishu-Somalia

open access: yesNeuropsychiatric Disease and Treatment, 2023
Mustafa Ali, Teresia Mutavi, John Maina Mburu, Muthoni Mathai Department of Psychiatry, University of Nairobi, Nairobi, KenyaCorrespondence: Mustafa Ali, Department of Psychiatry, School of Medicine, College of Health Sciences, University of Nairobi, P.O.
Ali M, Mutavi T, Mburu JM, Mathai M
doaj  

Cumulative trauma from multiple natural disasters increases mental health burden on residents of Fort McMurray

open access: yesEuropean Journal of Psychotraumatology, 2022
Background Fort McMurray, a city in northern Alberta, Canada, has experienced multiple traumatic events in the last five years, including the 2016 wildfire, the 2020 floods, and the COVID-19 pandemic.
Belinda Agyapong   +8 more
doaj   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Machine learning applications using diffusion tensor imaging of human brain: A PubMed literature review [PDF]

open access: yesarXiv, 2020
We performed a PubMed search to find 148 papers published between January 2010 and December 2019 related to human brain, Diffusion Tensor Imaging (DTI), and Machine Learning (ML). The studies focused on healthy cohorts (n = 15), mental health disorders (n = 25), tumor (n = 19), trauma (n = 5), dementia (n = 24), developmental disorders (n = 5 ...
arxiv  

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

Predictors of the co-occurrence of posttraumatic stress disorder and depressive disorder in psychiatric outpatients

open access: yesComprehensive Psychiatry, 2019
Introduction: We explored the predictors of co-occurring depressive disorder (DD) in individuals with posttraumatic stress disorder (PTSD) in an outpatient psychiatric setting.
Ji Young Choi
doaj  

Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine

open access: yesAdvanced Functional Materials, EarlyView.
Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang   +5 more
wiley   +1 more source

Quadripolar Relational Model: a framework for the description of borderline and narcissistic personality disorders [PDF]

open access: yesarXiv, 2015
Borderline personality disorder and narcissistic personality disorder are important nosographic entities and have been subject of intensive investigations. The currently prevailing psychodynamic theory for mental disorders is based on the repertoire of defense mechanisms employed.
arxiv  

Home - About - Disclaimer - Privacy