Results 71 to 80 of about 82,554 (326)
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang+6 more
wiley +1 more source
Elastic Shape Analysis of Brain Structures for Predictive Modeling of PTSD [PDF]
There is increasing evidence on the importance of brain morphology in predicting and classifying mental disorders. However, the vast majority of current shape approaches rely heavily on vertex-wise analysis that may not successfully capture complexities of subcortical structures.
arxiv
Mustafa Ali, Teresia Mutavi, John Maina Mburu, Muthoni Mathai Department of Psychiatry, University of Nairobi, Nairobi, KenyaCorrespondence: Mustafa Ali, Department of Psychiatry, School of Medicine, College of Health Sciences, University of Nairobi, P.O.
Ali M, Mutavi T, Mburu JM, Mathai M
doaj
Background Fort McMurray, a city in northern Alberta, Canada, has experienced multiple traumatic events in the last five years, including the 2016 wildfire, the 2020 floods, and the COVID-19 pandemic.
Belinda Agyapong+8 more
doaj +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Machine learning applications using diffusion tensor imaging of human brain: A PubMed literature review [PDF]
We performed a PubMed search to find 148 papers published between January 2010 and December 2019 related to human brain, Diffusion Tensor Imaging (DTI), and Machine Learning (ML). The studies focused on healthy cohorts (n = 15), mental health disorders (n = 25), tumor (n = 19), trauma (n = 5), dementia (n = 24), developmental disorders (n = 5 ...
arxiv
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan+4 more
wiley +1 more source
Introduction: We explored the predictors of co-occurring depressive disorder (DD) in individuals with posttraumatic stress disorder (PTSD) in an outpatient psychiatric setting.
Ji Young Choi
doaj
Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine
Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang+5 more
wiley +1 more source
Quadripolar Relational Model: a framework for the description of borderline and narcissistic personality disorders [PDF]
Borderline personality disorder and narcissistic personality disorder are important nosographic entities and have been subject of intensive investigations. The currently prevailing psychodynamic theory for mental disorders is based on the repertoire of defense mechanisms employed.
arxiv