Results 231 to 240 of about 109,890 (344)

Cumulative Trauma Disorders – "The Disease of the 90's": An Interdisciplinary Analysis

Juge, Denis Paul, Stokes, Harold M., Pine, John C.   +2 more
openalex   +2 more sources

Gender specific associations between potentially traumatic life events and mental health. [PDF]

Eur J Psychotraumatol
Schneider M, Traunmüller C, Rominger C, Čeplak K, Schwerdtfeger AR.   +4 more
europepmc   +1 more source

Epigenetic Targeting of Senescent Cells Prevents the Deleterious Effects of Obstructive Sleep Apnea on Growing Skeleton

Advanced Science, EarlyView.
Chronic intermittent hypoxia induces premature senescence of osteoprogenitor cells in long bone metaphysis via HIF1α‐mediated EZH2‐H3k27me3 downregulation, leading to impaired bone growth. Restoration of H3K27me3 level via UTX inhibition rescues osteogenesis and growth impairment in young mice.
Xiaonan Liu, Peilin Zhang, Zhongyi Su, Yong Feng, Zhenger Zhou, Sa Pang, Yicheng Wang, Jiacheng Hu   +7 more
wiley   +1 more source

The mediating roles of stressful life events and negative affect in the relationship between childhood maltreatment and non-suicidal self-injury among clinical adolescents. [PDF]

Eur J Psychotraumatol
He J, Chen Z, Shen Y, Tian Y, Li Y, Ou J.   +5 more
europepmc   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Complex trauma and perceived barriers to treatment among people accessing a supervised injecting facility. [PDF]

Eur J Psychotraumatol
Cheetham A, Lubman DI, Lam T, Grist E, Barnett A, Arunogiri S, Nielsen S.   +6 more
europepmc   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

The Effect of Childhood Psychological Abuse on Depressive Symptoms in Adolescents Exposed to Campus Suicide: The Chain Mediating Role of Psychological Trauma and Anxiety Symptoms. [PDF]

Behav Sci (Basel)
Tan T, Zhao J, Wu M, Zhang X, Liu X, Zhang L, Wu J.   +6 more
europepmc   +1 more source

A COMPARISON OF FLEXION AND EXTENSION EXERCISES IN WORKERS AT RISK FOR DEVELOPING CUMULATIVE TRAUMA DISORDER

, 2000
Joann K. Randolph
openalex   +1 more source

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source