Results 31 to 40 of about 9,587 (191)
Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou +12 more
wiley +1 more source
Capillary endothelial cell heterogeneity in skeletal muscle of female and male mice
Abstract In skeletal muscle, capillaries have been shown to be critical to active hyperemia by sensing skeletal muscle activity and directing blood flow to contracting muscle fibers. There is evidence to suggest that capillary endothelial cell (EC) characteristics may change along the length of a capillary.
Mackenzie E. Charter, Coral L. Murrant
wiley +1 more source
Tolerância a agente curarizante provocada pela administração repetida da droga
Baseados em teoria discutível segundo a qual a miastenia grave é provocada pela presença no sangue de substância curarizante liberada pelo timo, tentou-se reproduzir um modelo experimental.
Antonio Carlos Zanini +2 more
doaj +1 more source
Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang +4 more
wiley +1 more source
Evaluating Anesthetics for Improving Scientific Research and Welfare Using Larval Zebrafish
Using physiological and behavioral assays, we quantified the effectiveness and appropriateness of six commonly used fish anesthetics on zebrafish embryos. Different anesthetics performed better under different contexts. Figure prepared using BioRender.com.
Sylvia Dimitriadou +15 more
wiley +1 more source
Curatorial Ways of Making Cities and Navigating Futures Through Urban Experiments
Short Abstract Contemporary curation is profoundly relational, emphasising the importance of the interrelations amongst objects and the enhanced meanings generated through their dialogues with each other and with various publics. In this contribution, we outline a curatorial approach founded in relational geography to inform the co‐construction and ...
Miguel Valdez, Matthew Cook
wiley +1 more source
High gender -specific susceptibility to curare- a neuromuscular blocking agent
Curare, a selective skeletal muscle relaxant, has been used clinically to reduce shivering and as an anesthetic auxiliary in abdominal surgery. It is also widely used in animal experiments to block neuromuscular junction activity.
Santosh K Maurya +2 more
doaj
Background Efgartigimod, a human immunoglobulin G (IgG)1-derived Fc fragment targeting the neonatal Fc receptor, has been developed into intravenous (IV) and subcutaneous (SC) formulations for treating generalized myasthenia gravis (gMG) and other ...
Shan Jing +11 more
doaj +1 more source
Reviews of C. Beenfeldt, The Philosophical Background and Scientific Legacy of E. B. Titchener’s Psychology. Understanding Introspectionism, Springer 2013; Hyden-Hanscho, Pieper, Stangl (eds.), Cultural exchange and consumption patterns in the Age of ...
Roberto Gronda +2 more
doaj +1 more source

