, 2017 This paper evaluates the impact of various event extraction systems on automatic pathway curation using the popular mTOR pathway. We quantify the impact of training data sets as well as different machine learning classifiers and show that some improve ...
Kusa, Wojciech, Spranger, Michael
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
ShennongAlpha: an AI-driven sharing and collaboration platform for intelligent curation, acquisition, and translation of natural medicinal material knowledge [PDF]
, 2023 Zijie Yang +6 more
openalex +1 more source
Digital curation skills in the performing arts: an investigation of practitioner awareness and knowledge of digital object management and preservation [PDF]
, 2014 This study examines the digital curation awareness and practice of a sample of practitioners from the UK performing arts community. Twelve performance arts practitioners from across the United Kingdom were interviewed to establish understanding of ...
Molloy, Laura
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Editorial: Screening the Skin: Issues of Race and Nation in Screendance
The International Journal of Screendance, 2018 No abstract available.
Melissa Blanco Borelli, Raquel Monroe
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The fragility of curating a pioneer community: Deep mediatization and the spread of the Quantified Self and Maker movements [PDF]
, 2020 Andreas Hepp
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Towards a more sonically inclusive museum practice: a new definition of the ‘sound object’
Science Museum Group Journal, 2017 As museums continue to search for new ways to attract visitors, recent trends within museum practice have focused on providing audiences with multisensory experiences.
John Kannenberg
doaj +1 more source