Results 171 to 180 of about 46,151,458 (279)

Quick COVID-19 Severity Index, CURB-65 and Quick SOFA Scores Comparison in Predicting Mortality and Risk Factors of COVID-19 Patients. [PDF]

Arch Iran Med, 2022
Kılınç Toker A, Çelik İ, Toker İ, Eren E.   +3 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Improved prediction value of the CURB-65 score combined with the platelet-to-lymphocyte ratio for mortality in emergency department patients with severe community-acquired pneumonia. [PDF]

Front Med (Lausanne)
Lv C, Liu S, Yan Y, Ye Y, Gao Y, Zhou M.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Assessing pneumonia severity using neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios: a cross-sectional comparison with CURB-65 score. [PDF]

Ther Adv Infect Dis
Osama M, Iftikhar A, Abdul Baseer M, Khan N, Majid A, Amaraneni A, Anwer F, Thada PK.   +7 more
europepmc   +1 more source

A new predictive tool consolidating CURB-65 with procalcitonin and albumin to assess short-term mortality in hospitalized elderly patients with infectious disease: A retrospective study of a patient cohort. [PDF]

Medicine (Baltimore), 2022
Higashikawa T, Ito T, Mizuno T, Ishigami K, Kuroki K, Maekawa N, Usuda D, Nakao S, Hamada K, Takagi S, Terada N, Takeshima K, Yamada S, Sangen R, Izumida T, Kiyosawa J, Saito A, Iguchi M, Wato H, Nakahashi T, Kasamaki Y, Fukuda A, Kanda T, Okuro M.   +23 more
europepmc   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

An Audit Assessing Compliance With CURB-65 (Confusion, Urea, Respiratory Rate, Blood Pressure, and Age ≥65 Years) Documentation in Adult Patients Admitted With Community-Acquired Pneumonia at a Tertiary Institution in Trinidad and Tobago. [PDF]

Cureus
Ramlogan TV, Basdeo D, Bhagaloo R, De Freitas L.   +3 more
europepmc   +1 more source

Comparison of CURB-65 Pneumonia Severity Score, Quick COVID-19 Severity Index, and Brescia-COVID Respiratory Severity Scale in Emergently Hospitalized COVID-19 Patients with Pneumonia. [PDF]

Infect Dis Clin Microbiol, 2022
Toker İ, Kılınç-Toker A, Turunç-Özdemir A, Altuntaş M.   +3 more
europepmc   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source