Single cell measurement of telomerase expression and splicing using microfluidic emulsion cultures. [PDF]
, 2014 Telomerase is a reverse transcriptase that maintains telomeres on the ends of chromosomes, allowing rapidly dividing cells to proliferate while avoiding senescence and apoptosis.
Hart, Kristina +2 more
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Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice [PDF]
, 2017 Autophagy is usually a pro-survival mechanism in cancer cells, especially in the course of chemotherapy, thus autophagy inhibition may enhance the chemotherapy-mediated anti-cancer effect.
Bei, R. +10 more
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Turmeric and black pepper spices decrease lipid peroxidation in meat patties during cooking. [PDF]
, 2015 Spices are rich in natural antioxidants and have been shown to be potent inhibitors of lipid peroxidation during cooking of meat. Turmeric contains unique conjugated curcuminoids with strong antioxidant activity. Piperine, one of the main constituents of
Heber, David +6 more
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In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii [PDF]
, 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Betts, JW, Wareham, DW
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Curcumin-loaded zeolite as anticancer drug carrier: Effect of curcumin adsorption on zeolite structure [PDF]
, 2020 In this work we used a combination of different techniques to investigate the adsorption properties of curcumin by zeolite type A for potential use as an anticancer drug carrier.
Ahali Abadeh, Z. +3 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2007 【目的】为探讨姜黄素（curcumin）对胰岛素抵抗的治疗作用及其机制。【方法】利用胰岛素抵抗的小鼠模型,观察姜黄素对小鼠胰岛素抵抗的水平、转录因子I-κBα、循环细胞因子的变化。【结果】①姜黄素能抑制TNFα刺激Fao细胞NF-κB激活;②姜黄素治疗后小鼠的空腹血糖水平没有明显下降,但空腹胰岛素的水平下降约30%,葡萄糖耐量曲线的水平也明显下降;③循环中TNFα[（34.5±3.4）pg/mL vs（31.3±1.1）pg/mL]水平没有明显改变,而IL-1β[（33.9±3.2）pg/mL vs ...
郭颖, 高毅, 刘永光
doaj
Novel Findings about Double-Loaded Curcumin-in-HPβcyclodextrin-in Liposomes: Effects on the Lipid Bilayer and Drug Release [PDF]
, 2018 In this study, the encapsulation of curcumin (Cur) in “drug-in-cyclodextrin-in-liposomes (DCL)” by following the double-loading technique (DL) was proposed, giving rise to DCL–DL.
Fernández Romero, Ana María +4 more
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Natural Compounds as Beneficial Antioxidant Agents in Neurodegenerative Disorders: A Focus on Alzheimer’s Disease [PDF]
, 2019 The positive role of nutrition in chronic neurodegenerative diseases (NDs) suggests that dietary interventions represent helpful tools for preventing NDs.
Antonella Amato +2 more
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Zhongguo shiyan zhenduanxue, 2019 舌癌是口腔颌面部最常见的恶性肿瘤,治疗比较棘手[1],因此有必要进一步研究舌癌的发病抑制以及发现及探求有价值的治疗药物,为舌癌的治疗提供依据。姜黄素(curcumin)是从草本植物姜黄根茎中提取出的一种酚性色素,具有抗肿瘤,抗氧化,抗突变等多种生物学作用,且毒副作用小,获取方便,对多种肿瘤细胞增殖有明显抑制作用[2]。因此 ...
金月, 金明光, 魏来, 崔云峰
doaj
Antidiabetic effect of Tibetan medicine Tang-Kang-Fu-San on high-fat diet and streptozotocin-induced type 2 diabetic rats [PDF]
, 2017 The aim of this study was to investigate the antidiabetic effects of a Tibetan medicine, Tang-Kang-Fu-San (TKFS), on experimental type 2 diabetes mellitus (T2DM) rats and to explore its underlying mechanisms.
Duan, Bailu +8 more
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