Results 11 to 20 of about 617,754 (317)

Awareness screening and referral patterns among pediatricians in the United States related to early clinical features of spinal muscular atrophy (SMA)

BMC Pediatrics, 2021
Background Spinal Muscular Atrophy (SMA), a leading genetic cause of death in infants, is an autosomal recessive neuromuscular disease characterized by progressive muscle weakness and atrophy. While early diagnosis of SMA is critical to modifying disease
Mary Curry, Rosángel Cruz, Lisa Belter, Mary Schroth, Megan Lenz, Jill Jarecki   +5 more
doaj   +1 more source

“I have SMA, SMA doesn’t have me”: a qualitative snapshot into the challenges, successes, and quality of life of adolescents and young adults with SMA

Orphanet Journal of Rare Diseases, 2021
Background With the approval of three treatments for spinal muscular atrophy (SMA) and several promising therapies on the horizon, the SMA adolescent and young adult populations are expected to evolve in the coming years.
Allison Mazzella, Mary Curry, Lisa Belter, Rosángel Cruz, Jill Jarecki   +4 more
doaj   +1 more source

Effects of the COVID-19 Pandemic on SMA Screening and Care: Physician and Community Insights

Neurology and Therapy, 2023
Objective As part of efforts to reduce diagnostic delays and enhance clinical trials, Cure SMA evaluated the effects of COVID-19 on SMA care and clinical trial conduct.
Mary Curry, Ilse Peterson, Lisa Belter, Fatou Sarr, Sarah Whitmire, Mary Schroth, Jill Jarecki   +6 more
doaj   +1 more source

Strong relationship between cholesterol, low-density lipoprotein receptor, Na+/H+ exchanger, and SARS-COV-2: this association may be the cause of death in the patient with COVID-19

Lipids in Health and Disease, 2021
Lipids have a wide variety and vital functions. Lipids play roles in energy metabolism, intracellular and extracellular signal traffic, and transport of fat-soluble vitamins. Also, they form the structure of the cell membrane.
Erkan Cure, Medine Cumhur Cure
doaj   +1 more source

CURE Newsletter Issue 5

, 2022
The 5th issue of the CURE Newsletter presents the progress and the main achievements of the CURE project during the first half of 2022 as well as includes detailed descriptions of three more CURE applications: Urban Heat Storage Monitoring ...
CURE H2020 project
core   +1 more source

CURE Newsletter Issue 4

, 2021
The 4th issue of the CURE Newsletter presents the progress and the main achievements of the CURE project during the second half of 2021 as well as includes detailed descriptions of three more CURE applications: Urban Flood Risk Application Urban Air ...
CURE H2020 project
core   +1 more source

Barranquilla, la casa de todos

Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2017
Extracto Barranquilla es la primera ciudad de Colombia en el ranking de ciudades del futuro y la séptima del continente según el periódico británico Financial Times en su informe para el periodo 2017-2018 de su Centro de Investigaciones, en el que ...
Carlos Cure Cure
doaj   +1 more source

Deep brain stimulation of the Cuneiform nucleus for levodopa-resistant freezing of gait in Parkinson’s disease: study protocol for a prospective, pilot trial

Pilot and Feasibility Studies, 2021
Background Freezing of gait (FOG) is a particularly debilitating motor deficit seen in a subset of Parkinson’s disease (PD) patients that is poorly responsive to standard levodopa therapy or deep brain stimulation (DBS) of established PD targets such as ...
Stephano J. Chang, Iahn Cajigas, James D. Guest, Brian R. Noga, Eva Widerström-Noga, Ihtsham Haq, Letitia Fisher, Corneliu C. Luca, Jonathan R. Jagid   +8 more
doaj   +1 more source

A Richness that Cures [PDF]

Neuron, 2007
A study in Nature by Fischer et al. shows that environmental enrichment or increasing histone acetylation rescue the ability to form new memories and re-establish access to remote memories even in the presence of brain degeneration. Chromatin remodeling may be the final gate environmental enrichment opens to enhance plasticity and represents a ...
PIZZORUSSO, TOMMASO, BERARDI, NICOLETTA, MAFFEI L.   +2 more
openaire   +5 more sources

Quality of life data for individuals affected by spinal muscular atrophy: a baseline dataset from the Cure SMA Community Update Survey

Orphanet Journal of Rare Diseases, 2020
Background Individuals and/or caregivers of individuals affected by spinal muscular atrophy (SMA) completed the 2019 Cure SMA Community Update Survey, online, assessing health-related quality of life (HRQoL), loss of work productivity, and fatigue using ...
Lisa Belter, Rosángel Cruz, Jill Jarecki   +2 more
doaj   +1 more source