Results 61 to 70 of about 617,754 (317)

The Role of Pannexin-1 Channels in HIV and NeuroHIV Pathogenesis

open access: yesCells, 2022
The human immunodeficiency virus-1 (HIV) enters the brain shortly after infection, leading to long-term neurological complications in half of the HIV-infected population, even in the current anti-retroviral therapy (ART) era. Despite decades of research,
Cristian A. Hernandez, Eugenin Eliseo
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Stochastic simulation of the cure of advanced composites [PDF]

open access: yes, 2015
This study focuses on the development of a stochastic simulation methodology to study the effects of cure kinetics uncertainty, in plane fibre misalignment and boundary conditions uncertainty on the cure process of composite materials.
Mesogitis, Tassos
core  

Enhancing sudden unexpected death in epilepsy (SUDEP) research through development of common data elements

open access: yesEpilepsia Open
Objective Sudden Unexpected Death in Epilepsy (SUDEP) is a fatal complication for individuals living with epilepsy and is associated with significant personal and public burden.
Sloka S. Iyengar   +6 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Monitoring and Heat Transfer Modelling of the Cure of Thermoset Composites Processed by Resin Transfer Moulding. [PDF]

open access: yes, 1999
Experimental studies have demonstrated the existence of significant thermal gradients during the cure stage of Resin Transfer Moulding (RTM). Presence of such thermal gradients can affect the final degree-of-cure distribution and cause the development
Skordos, Alexandros A.   +1 more
core  

Copernicus Core Services Interface - Documentation (CURE Deliverable D2.2)

open access: yes, 2020
This document presents a technical description of the CURE Copernicus Core Services Interface (CCSI) and its implementation. The aim of this development activity is to provide a unified interface to streamline search and locate Copernicus services ...
Opletal, Michal
core   +1 more source

Emerging risks of lipid-lowering therapy and low LDL levels: implications for eye, brain, and new-onset diabetes

open access: yesLipids in Health and Disease
Atherosclerotic cardiovascular disease remains a major global health burden. Current guidelines emphasize aggressive lipid-lowering strategies, particularly those that reduce low-density lipoprotein cholesterol (LDL-C) levels. While effective in lowering
Erkan Cure, Medine Cumhur Cure
doaj   +1 more source

Let's Get Back to Normal? COVID-19 and the Logic of Cure

open access: yesFrontiers in Sociology, 2022
The COVID-19 pandemic has inversed certainties of absolutes of cure in everyday life but paradoxically this has occurred during a time when novel scientific advancements seem to herald a new frontier of cures for rare diseases, chronic conditions ...
Maria Berghs
doaj   +1 more source

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