Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The phenomenological model of 5429 resin was established by cure kinetic parameters of the bismaleimide (5429) with double-heating wave reaction characteristics gained by dynamic DSC analysis combining with the phenomenological model.
ZHANG Chen-qian +4 more
doaj +1 more source
Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine During Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania. [PDF]
The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and ...
Annerberg, Anna +10 more
core +4 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Exploiting limited valence patchy particles to understand autocatalytic kinetics [PDF]
Autocatalysis, i.e., the speeding up of a reaction through the very same molecule which is produced, is common in chemistry, biophysics, and material science. Rate-equation-based approaches are often used to model the time dependence of products, but the
Corezzi, Silvia +2 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Motivated by the widespread and contradictory results regarding the glass transition temperature of carbon nanotube (CNT)/epoxy composites, we reviewed and analyzed the literature results dealing with the effect of unmodified multiwall carbon nanotubes ...
doaj +1 more source
Autoclave molding of prepregs is an established fabrication method to produce composite components to be used in the aerospace industry and elsewhere. The process involves the excess resin to flow out and curing of the resin. The process model simulation,
Maji Prosenjit, Neogi Swati
doaj +1 more source
Sequential curing of amine-acrylate-methacrylate mixtures based on selective aza-Michael addition followed by radical photopolymerization [PDF]
Dual curing systems find various uses in industry with the process flexibility they provide which allows tailoring properties at different curing stages in accordance with application requirements. A safe and efficient dual curing scheme is proposed here
Fernández Francos, Xavier +3 more
core +1 more source
Investigating the impact of curing system on structure-property relationship of natural rubber modified with brewery by-product and ground tire rubber [PDF]
The application of wastes as a filler/reinforcement phase in polymers is a new strategy to modify the performance properties and reduce the price of biocomposites.
Cañavate Ávila, Francisco Javier +5 more
core +3 more sources

