Results 121 to 130 of about 486,644 (292)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Applied MechanicsComposite curing through infrared radiation (IR) has become a popular autoclave alternative due to lower energy costs and short curing cycles. As such, understanding and measuring the effect of all parameters involved in the process can aid in selecting ...
Petros Gkertzos +3 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Case Studies in Construction MaterialsAdding fibres can help increase the performance of the binder and, thus, the mechanical performance of the pervious concrete. However, their performance under various curing conditions is questionable.
Jie Li +3 more
doaj +1 more source
Adhesive joint evaluation by ultrasonic interface and lamb waves [PDF]
Some results on the application of interface and Lamb waves for the study of curing of thin adhesive layers were summarized. In the case of thick substrates (thickness much more than the wave length) the interface waves can be used.
Rokhlin, S. I.
core +1 more source
Sprayable birefringent coating enables strain measurements on large surfaces [PDF]
, 1966 Birefringent coating for strain measurements on large surfaces contains constituents that can be premixed and sprayed as a single component with conventional paint spray equipment.
Humphrey, F. T., Mc~gee, W. M.
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Solidification of APC residues using PFA
, 2009 A pulverised fuel ash (pfa) classed as a waste due to high loss on ignition (LoI) was blended with waste alkali and used to solidify air pollution control (APC) residue from a waste incinerator.
Black, L, Shirley, R
core