Results 81 to 90 of about 486,644 (292)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Method for applying photographic resists to otherwise incompatible substrates [PDF]

open access: yes, 1981
A method for applying photographic resists to otherwise incompatible substrates, such as a baking enamel paint surface, is described wherein the uncured enamel paint surface is coated with a non-curing lacquer which is, in turn, coated with a partially ...
Fuhr, W.
core   +1 more source

Electrical conductivity of carbon nanofiber reinforced resins: potentiality of Tunneling Atomic Force Microscopy (TUNA) technique [PDF]

open access: yes, 2003
Epoxy nanocomposites able to meet pressing industrial requirements in the field of structural material have been developed and characterized. Tunneling Atomic Force Microscopy (TUNA), which is able to detect ultra-low currents ranging from 80 fA to 120 ...
Raimondo1, Marialuigia   +8 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Curing America\u27s Addiction to Prisons [PDF]

open access: yes, 1993
Our prisons have failed society because they do not, generally, provide an experience that is likely to help offenders overcome the obstacles that led them to make mistakes for which they are now being punished.
Leven, David C.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The Cost of Uncertainty in Curing Epidemics

open access: yes, 2018
Motivated by the study of controlling (curing) epidemics, we consider the spread of an SI process on a known graph, where we have a limited budget to use to transition infected nodes back to the susceptible state (i.e., to cure nodes).
Caramanis, Constantine   +1 more
core   +1 more source

Estimation of corrosion resistance of curing mixtures based on coal-bearing rocks from Western Donbass [PDF]

open access: yes, 2016
Purpose. Substantiation of possible use of coal-bearing rocks as a replacement for a part of the filler in the preparation of shotcrete for lining of mine workings in the conditions of mineralized mine water. Methods.
Harkusha, V, Kovalenko, V
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Improved cure method for single component silicone rubber [PDF]

open access: yes, 1969
Water is incorporated in a carrier and then thoroughly mixed with the single component silicone rubber containing acetic anhydride as a curing agent.
Lippitt, M. W.
core   +1 more source

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