Results 161 to 170 of about 569,836 (364)

Curing America\u27s Addiction to Prisons [PDF]

, 1993
Our prisons have failed society because they do not, generally, provide an experience that is likely to help offenders overcome the obstacles that led them to make mistakes for which they are now being punished.
Leven, David C.
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

A Study of Fifty Consecutive Cases of Operation for the Radical Cure of Non-Strangulated Hernlæ [PDF]

, 1890
A. E. Barker
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

THE RESULTS OF OPERATIONS FOR THE CURE OF CANCER OF THE BREAST PERFORMED AT THE JOHNS HOPKINS HOSPITAL FROM JUNE, 1889, TO JANUARY, 1894 [PDF]

, 1894
W. S. Halsted
openalex   +1 more source

CURE OF HERNIA. [PDF]

The Lancet
n ...
openaire   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

A NEW PRINCIPLE OF CURING CLUB-FOOT IN SEVERE CASES IN CHILDREN A FEW YEARS OLD [PDF]

, 1902
Alex. Ogston
openalex   +1 more source

Effect of Incorporating Natural Zeolitic Tuffs in Concrete Mixed and Cured Using Seawater

Eng
Concrete production has increasingly used seawater to overcome the challenge of freshwater scarcity. Although the use of seawater in concrete still has a controversial reputation, it is a promising application, particularly when combined with mineral ...
Ansam Qsymah, Hasan Alqawasmeh, Mo’men Ayasrah, Buthainah Al-kharabsheh   +3 more
doaj   +1 more source

A Bayesian promotion time cure model with current status data [PDF]

arXiv
Analysis of lifetime data from epidemiological studies or destructive testing often involves current status censoring, wherein individuals are examined only once and their event status is recorded only at that specific time point. In practice, some of these individuals may never experience the event of interest, leading to current status data with a ...
arxiv