Results 101 to 110 of about 112,173 (343)

Evaluation of in-situ shrinkage and expansion properties of polymer composite materials for adhesive anchor systems by a novel approach based on digital image correlation [PDF]

, 2019
The curing reaction of thermosetting resins is associated with chemical shrinkage which is overlapped with thermal expansion as a result of the exothermal enthalpy. Final material properties of the polymer are determined by this critical process.
Lichtenegger, Helga C., Singer, Gerald, Sinn, Gerhard, Veigel, Stefan, Wan-Wendner, Roman, Zecchini, Michele   +5 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Fatigue life extension of epoxy materials using ultrafast epoxy-SbF5 healing system introduced by manual infiltration

eXPRESS Polymer Letters, 2015
The present paper is devoted to the verification of the capability of epoxy-SbF5 system as a healing chemistry for rapidly retarding and/or arresting fatigue cracks in epoxy materials at room temperature.
X. J. Ye, Y. Zhu, Y. C. Yuan, Y. X. Song, G. C. Yang, M. Z. Rong, M. Q. Zhang   +6 more
doaj   +1 more source

Mechanical Properties of Microstructural Components of Inorganic Materials [PDF]

, 2013
Disertační práce se zabývá studiem strukturních a mechanických vlastností anorganických materiálů. Cílem je nalezení jednotlivých fází ve zkoumaném materiálu a hlavně lokalizace (mechanicky) nejslabšího místa, jeho ovlivnění a následně výroba materiálu o
Wasserbauer, Jaromír
core  

An adaptive neuro fuzzy inference system to model the uniaxial compressive strength of cemented hydraulic backfill [PDF]

, 2018
Purpose. The purpose of this paper is to develop the models for predicting the uniaxial compressive strength (UCS) of cemented hydraulic backfill (CHB), a widely used technique for filling underground voids created by mining operations as it provides ...
Basarir, H, Bin, H, Elchalakani, M, Fourie, A, Karrech, A   +4 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Polyoxazolines with an Imidazole Terminal Group as Thermal Latent Curing Agents for One‐Component Epoxy Resins

Macromolecular Materials and Engineering
Poly(2‐oxazoline)‐imidazole (POZ‐Im) polymers were synthesized by one‐pot termination of 2‐ethyl, 2‐propyl‐, and 2‐phenyl‐2‐oxazoline homopolymers with imidazole and evaluated as thermal latent curing agents (TLCs) for one‐component epoxy resins (OCERs).
Ceren Ozsaltik, Cuma Ali Uçar, Asu Ece Atespare, Bekir Dizman   +3 more
doaj   +1 more source

Biopolymer stabilization of clayey soil

Journal of Rock Mechanics and Geotechnical Engineering
This study investigates the efficacy of sodium alginate (SA), xanthan gum (XG), guar gum (GG) and chitosan (CS) — each applied at five different solid biopolymer-to-water mass ratios (or dosages) and cured for 7 d and 28 d — on the unconfined compressive
Mahdieh Azimi, Amin Soltani, Mehdi Mirzababaei, Mark B. Jaksa, Nanjappa Ashwath   +4 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source