Results 131 to 140 of about 105,966 (325)

Role of Curing Conditions and Precursor on the Microstructure and Phase Chemistry of Alkali-Activated Fly Ash and Slag Pastes [PDF]

, 2021
Marija Nedeljković, Bahman Ghiassi, Guang Ye   +2 more
openalex   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Characteristics and preliminary healing ability of polydimethylsiloxane elastomers

Journal of Materials Research and Technology
Flexible polydimethylsiloxane (PDMS)-based elastomers are extensively used in microfluidics and microelectronics due to their exceptional thermal stability, chemical inertness, flexibility, and stretchability.
Thi Sinh Vo, Truong Sinh Nguyen, Byounghyun Jeon, Tran Thi Bich Chau Vo, Soobean Han, Seung-Hyun Lee, Kyunghoon Kim   +6 more
doaj  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Green chemistry gets the prize | PBDEs in electronics-recycling workers in China | E-waste recycling spews dioxins into the air | Investing in renewable energy | Mixed reports on EU industrial pollutants | Battling climate change the American way | Nuclear energy: not a climate cure | Shift urged for chemical toxicity testing | Sustainable coal use | Environmental costs of desalination | The muddy waters of wetland protection [PDF]

, 2007
Naomi Lubick, KELLYN BETTS, Rhitu Chatterjee, KRIS CHRISTEN   +3 more
openalex   +1 more source

The Design and Implementation of an Interdisciplinary CURE as an Alternative Option for the General Chemistry Laboratory Course

, 2022
Dean Miller, Angela Natale, Tatiana K. McAnulty, Rachel D. Swope, Emily A. McNaughton, Aviauna Beckett, Hannah E. Snoke, Annalee M. Schmidt, John N. Alumasa, Shawn Xiong   +9 more
openalex   +2 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

The Effects of Internal Curing and Shrinkage Cracking Avoidance on the Corrosion of Reinforced Concrete Walls with Superabsorbent Polymers

Applied Sciences
The pursuit of durable and sustainable construction has driven interest in innovative materials, with superabsorbent polymers (SAPs) emerging as a promising solution, especially for the concrete industry. SAPs offer significant benefits to the durability
José Roberto Tenório Filho, Nele De Belie, Didier Snoeck   +2 more
doaj   +1 more source