Results 141 to 150 of about 109,294 (342)
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang +6 more
wiley +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu +12 more
wiley +1 more source
Using a polyester binder for the interlaminar toughening of glass/epoxy composite laminates [PDF]
Bisphenol A based polyester is commonly used in the industry as a binder, or tackifier, to produce cost-saving preforms in Liquid Composite Moulding processes such as Vacuum Assisted Resin Transfer Moulding (VARTM). However, it is often reported that the
Daelemans, Lode +5 more
core +1 more source
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
Composition and performance driven mix design methodology for geopolymer mortars
Geopolymers are gaining attention as sustainable alternatives to conventional cement due to their significantly lower environmental impact. However, mix design remains challenging due to the complex interactions between precursors and alkaline activators.
Anuoluwapo Sola Kolade +2 more
doaj +1 more source
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
wiley +1 more source
Use of superabsorbent polymers to mitigate autogenous shrinkage in ultra-high performance concrete [PDF]
Ultra-high performance concrete (UHPC) with low w/c-ratio is very prone to the formation of cracks due to autogenous shrinkage. These cracks can lead to a decreased durability of the concrete, resulting in higher maintenance and/or repair costs in the ...
De Belie, Nele +5 more
core
Chemistry of dihydrophenanthrene ketal and its application in polymer curing.
Abdul Munam
openalex +2 more sources

