Results 151 to 160 of about 105,966 (325)
Molecular Oncology, EarlyView.Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley +1 more source
Abstract 2151 First Year Chemistry CURE: An Introduction to Chemical Thinking through the Lens of Antimalarial Drug Design [PDF]
Jessica Bell +3 more
openalex +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Effect of substituted phenylnadimides on processing and properties of PMR polyimide composites [PDF]
Three nitrophenylnadimide cure initiators and two phenylnadimides (without nitros) were evaluated as additives to PMR-15 resins and Celion 6000 graphite fiber composites.
Alston, W. B., Lauver, R. W.
core +1 more source
International Journal of Nanomedicine, 2015 Jian Wang,1 Yi Zuo,1 Minghui Zhao,1 Jiaxing Jiang,1 Yi Man,2 Jun Wu,3 Yunjiu Hu,3 Changlei Liu,4 Yubao Li,1 Jidong Li11Research Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu, Sichuan, People’s Republic of ...
Wang J +9 more
doaj
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
On-line mass spectrometric monitoring of the polymerization of a phenolic-resin-based material [PDF]
Polymerization of phenolic-resin-based materials requires elevated temperatures. The low thermal conductivity of these materials has led to the use of dielectric heating techniques in lieu of standard convection oven heating to obtain a satisfactory cure.
Aikens, D. A. +2 more
core +1 more source
3D printing of polybutadiene rubber cured by photo-induced thiol-ene chemistry: A proof of concept
, 2020 Mario Bragaglia +3 more
openalex +1 more source
Stimulating Students’ Learning in Analytical Chemistry through an Environmental-Based CURE Project
, 2021 Grace W. Muna
openalex +2 more sources