Results 191 to 200 of about 1,567,888 (364)

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Unveiling the combined influence of higher molecular weight polyethylene glycol and superplasticizer chemistry on fresh, mechanical, and microstructural performance of internally cured mortar

K. Raghavendra Ravi Kiran, Dhanya Sathyan   +1 more
openalex   +1 more source

Fragment-Based Ligand Discovery Using Protein-Observed ¹⁹F NMR: A Second Semester Organic Chemistry CURE Project

, 2021
Scott K. Bur, William C. K. Pomerantz, Morgan L. Bade, Clifford T. Gee   +3 more
openalex   +2 more sources

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Study on the Rheological Properties of BGAP Adhesive and Its Propellant. [PDF]

Molecules
Shao Y, Xu S, Xu H, Xie W, Zhang Z, Yao E, Jiang H.   +6 more
europepmc   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

The Chemistry of Behind the UV-Curable Nail Polishes. [PDF]

Polymers (Basel)
Mieriņa I, Grigale-Sorocina Z, Birks I.
europepmc   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

Effects of carbon nanotube and curing agent concentrations on the mechanical, thermal and electrical properties of polydimethylsiloxane: optimization and statistical analysis. [PDF]

RSC Adv
Laftah WA, Wan Abdul Rahman WA, Ibrahim AN.   +2 more
europepmc   +1 more source

The exploration of Michael-addition reaction chemistry to create high performance, ambient cure thermoset coatings based on soybean oil

, 2017
Adlina Paramarta, Dean C. Webster
openalex   +2 more sources