Results 131 to 140 of about 309,826 (311)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Curing behavior and properties of stator bar surface paints under infrared radiation

open access: yesFushe yanjiu yu fushe gongyi xuebao
Stator bars are crucial components in motor production. The traditional process used for curing the surface paint of stator bars has a long cycle, low efficiency, and high energy consumption.
HAN Jinhui   +7 more
doaj   +1 more source

Kecerdasan emosi dalam kalangan pelajar Diploma Pendidikan Lepasan Ijazah (DPLI) Universiti Tun Hussein Onn Malaysia [PDF]

open access: yes, 2013
Kecerdasan emosi dapat dijadikan sebagai panduan bagi mewujudkan pendidikan yang berkualiti serta sebagai asas pemerolehan ilmu pengetahuan bagi seseorang pendidik dalam menjalankan tugasnya sebagai seorang guru.
Che Ani, Rashida
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

[Curing method affecting the formation of oxygen inhibition layer on the surface of resin cement]. [PDF]

open access: yesBeijing Da Xue Xue Bao Yi Xue Ban, 2020
Chen WX, Bao XD, Yue L.
europepmc   +1 more source

Polymer of phosphonylmethyl-2,4- and -2,6-diamino benzene and polyfunctional monomer [PDF]

open access: yes, 1986
A phosphonyl methyl benzene is prepared by nitration to produce a 2,4-dinitro phosphonyl methyl benzene, which is then reduced to a diamino compound. The diamino compound is then used to cure a polymerizable monomer.
Kourtides, D. A., Mikroyannidis, J. A.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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