Results 141 to 150 of about 309,826 (311)

Design and test of controlling frequency circulating fan system in bulk curing barn

Heliyon
Objective: Scientific control of wind speed between tobacco leaves can improve quality of tobacco after cured in bulk curing barn. Method: Regarding the light orange color after cured tobacco and high power consumption caused by inaccurate control of the
Jianan Wang, Guangting Yin, Xiaolong Chen, Hongtao Shen, Weidong Duan   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Water absorption and curing time performance of urea formaldehyde resin mixed with different amount phosphorous-based fire retardants. [PDF]

, 2008
The curing time and the properties of urea formaldehyde (UF) resin mixed with fire retardants, BP (mixture of boric acid, guanylurea phosphate and phosphoric acid), monoammonium phosphate (MAP) and diammonium phosphate (DAP) were studied. There were two
Abdul Malek, Abdul Rashid, Abood, Faizah, Ashaari, Zaidon, Kamal, Izran, Misran, Suffian, Rusli, Rafeadah, Saad, Mohamad Jani, Thirmizir, Mohd Zharif   +7 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Fiber Bragg grating in-situ detection method for curing characteristics of GIS epoxy/Al2O3 composite insulation materials

Polymer Testing
Excessive residual strain generated by curing shrinkage of epoxy/Al2O3 composite insulation materials can reduce the mechanical properties of gas-insulated metal-enclosed switchgear (GIS) insulators.
Yingying Zhang, Yanpeng Hao, Zikui Shen, Dongyuan Du, Hongru Mi   +4 more
doaj   +1 more source

Process for improving mechanical properties of epoxy resins by addition of cobalt ions [PDF]

, 1984
A resin product useful as an adhesive, composite or casting resin is described as well as the process used in its preparation to improve its flexural strength mechanical property characteristics.
St.clair, A. K., Stoakley, D. M.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Process for preparing sterile solid propellants Patent [PDF]

, 1967
Using ethylene oxide in preparation of sterilized solid rocket propellants and encapsulating ...
Montgomery, L. C., Morelli, F. A.
core   +1 more source