Results 71 to 80 of about 309,826 (311)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Flexural Behaviour Of High Performance Slurry Infiltrated Fiber Reinforced Concerete With Different Curing Method. [PDF]

, 2013
In the conventional steel fiber reinforced concrete, the structure is fabricated by combining steel fiber to the concrete mix. By using this method, the volume fraction of fiber is limited.
Abd. Aziz, Farah Nora Aznieta, Abdul Rahim, Mustaqqim, Md Ghazaly, Zuhayr, Mohamad Ibrahim, Norlia, Shahidan, Shahiron   +4 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Effects of Different Pickling Methods on the Water Retention and Protein Oxidation of Salted Goose Raw Material

Shipin gongye ke-ji
This study aimed to investigate the impact of different pickling methods on the water retention and protein structure of salted goose raw material. Five pickling methods, namely conventional curing, vacuum tumbling curing, ultrasound curing, ultrasound ...
Huan ZHANG, Zhicheng XU, Zhaoli ZHANG, Chuanming HUAN, Donghui GAO, Chang SU, Xiangren MENG   +6 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Experimental study on replacement of fine aggregate in concrete with dissimilar curing conditions

Case Studies in Construction Materials, 2019
The nation over, Scarcity of natural sand, water, and craftsmanship is at the zenith in the construction sectors. The construction industries are now inquiring other substitutes.
T. Devadass
doaj   +1 more source

Electrical conductivity of carbon nanofiber reinforced resins: potentiality of Tunneling Atomic Force Microscopy (TUNA) technique [PDF]

, 2003
Epoxy nanocomposites able to meet pressing industrial requirements in the field of structural material have been developed and characterized. Tunneling Atomic Force Microscopy (TUNA), which is able to detect ultra-low currents ranging from 80 fA to 120 ...
Raimondo1, Marialuigia, Guadagno, Liberata, Vertuccio, Luigi, Naddeo, Carlo, Barra, Giuseppina, Spinelli, Giovanni, Lamberti, Patrizia, Tucci, Vincenzo, Lafdi, Khalid   +8 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of Curing Methods on Efficiency of Curing of Cement Mortar

APCBEE Procedia, 2014
AbstractAdvancements in construction and chemical industry have paved a way for development of new curing techniques Significant amount of research has been conducted to evaluate curing effectiveness and its effect on various concrete properties. This paper synthesizes findings from the literature review and experimental investigation carried out as ...
Nahata, Yash, Kholia, Nirav, Tank, T.G.
openaire   +1 more source