Results 111 to 120 of about 320,301 (288)

IoT-Driven Innovations in Concrete Curing: Advancing Sustainable Construction with Hot Water Curing [PDF]

E3S Web of Conferences
Curing is a critical process in concrete construction, ensuring adequate hydration for achieving the desired strength and durability. However, traditional methods, such as 28-day water curing, are often resource-intensive and misaligned with the fast ...
Manoj Tangudu, Sai Vaddi Sesha, Prasad D.R., Tadepalli Tezeswi, Rao T. Muralidhara, Bommisetty Jagadeesh   +5 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Raman and nuclear magnetic resonance investigation of alkali metal vapor interaction with alkene-based anti-relaxation coating

, 2016
The use of anti-relaxation coatings in alkali vapor cells yields substantial performance improvements by reducing the probability of spin relaxation in wall collisions by several orders of magnitude.
Balabas M., D. Budker, Günther H., J. W. Blanchard, Jackson D. F., M. V. Balabas, Mistry B., O. Yu. Tretiak, P. K. Olshin, Robinson H., S. N. Smirnov, Socrates G., Woodward R. B.   +12 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

The impact of various curing methods on the curing process of polymer-fiber composites analyzed using analytical approach

Results in Engineering
Ti/Gf/Cf represents a novel form of hybrid fiber metal laminates (HFMLs) that successfully blend the benefits of titanium alloy, glass fiber reinforced plastic (GFRP), and carbon fiber reinforced plastic (CFRP). These materials have garnered attention in
Mohammadmahdi Negaresh, Hossein Nazockdast, Ali Asghar Katbab   +2 more
doaj   +1 more source

Low-cost technology for the integration of micro- and nanochips into fluidic systems on printed circuit board: fabrication challenges [PDF]

, 2012
Nowadays, micro- and nanochips are usually\ud fabricated with Silicon and/or glass. A simple, low-cost and\ud reliable integration packaging method that provides flexibility\ud to the incorporation of electronic and fluidic devices into a\ud system has ...
Akkerman, R., Bastemeijer, J., Bossche, A., Mokkapati, V.R.S.S., Mollinger, J.R., Palacios-Aguilera, N.B., Visser, H.A.   +6 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Process for preparing sterile solid propellants Patent [PDF]

, 1967
Using ethylene oxide in preparation of sterilized solid rocket propellants and encapsulating ...
Montgomery, L. C., Morelli, F. A.
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source