Results 61 to 70 of about 10,455 (248)
A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice
eLife, 2020 Amyloids are a class of protein with unique self-aggregation properties, and their aberrant accumulation can lead to cellular dysfunctions associated with neurodegenerative diseases. While genetic and environmental factors can influence amyloid formation,
Timothy R Sampson +15 more
doaj +1 more source
Biofilm, 2021 Biofilms enable bacteria to colonize numerous ecological niches. Bacteria within a biofilm are protected by the extracellular matrix (ECM), of which the fibril-forming amyloid protein curli and polysaccharide cellulose are major components in members of ...
Ferdinand X. Choong +8 more
doaj +1 more source
The role of bacterial secretion systems in the virulence of Gram-negative airway pathogens associated with cystic fibrosis [PDF]
, 2016 Cystic fibrosis (CF) is the most common lethal inherited disorder in Caucasians. It is caused by mutation of the CF transmembrane conductance regulator (CFTR) gene.
Depluverez, Sofie +2 more
core +2 more sources
Journal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron +3 more
wiley +1 more source
Statistical Mechanical Treatments of Protein Amyloid Formation [PDF]
, 2013 Protein aggregation is an important field of investigation because it is closely related to the problem of neurodegenerative diseases, to the development of biomaterials, and to the growth of cellular structures such as cyto-skeleton. Self-aggregation of
Schreck, John S., Yuan, Jian-Min
core +3 more sources
Congo Red Interactions with Curli-Producing E. coli and Native Curli Amyloid Fibers. [PDF]
PLoS ONE, 2015 Microorganisms produce functional amyloids that can be examined and manipulated in vivo and in vitro. Escherichia coli assemble extracellular adhesive amyloid fibers termed curli that mediate adhesion and promote biofilm formation.
Courtney Reichhardt +6 more
doaj +1 more source
Surface adhesins and exopolymers of selected foodborne pathogens [PDF]
, 2014 The ability of bacteria to bind different compounds and to adhere to biotic and abiotic surfaces provides them with a range of advantages, such as colonization of various tissues, internalisation, avoidance of an immune response and survival and ...
Agnes Weiss +45 more
core +2 more sources
Enterobacter Species: Opportunistic Human and Plant Pathogens With Plant‐Beneficial Traits
Molecular Plant Pathology, Volume 27, Issue 3, March 2026.The pathogen profile on Enterobacter species synthesises current knowledge on host range, disease symptoms, plant‐beneficial traits and compares genomic features within the genus. ABSTRACT Enterobacter species occur across diverse habitats and are best known for causing opportunistic and nosocomial infections in humans.
Sara Jordan +3 more
wiley +1 more source
Small regulatory RNAs control the multi-cellular adhesive lifestyle of Escherichia coli [PDF]
, 2012 Small regulatory RNA molecules have recently been recognized as important regulatory elements of developmental processes in both eukaryotes and bacteria. We here describe a striking example in Escherichia coli that can switch between a single-cell motile
Boysen, Anders +5 more
core +1 more source
Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore
Advanced Functional Materials, Volume 36, Issue 15, 19 February 2026.To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul +8 more
wiley +1 more source