Results 61 to 70 of about 6,556 (206)

Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae.

PLoS Biology, 2020
Curli play critical roles in biofilm formation, host cell adhesion, and colonization of inert surfaces in many Enterobacteriaceae. In Escherichia coli, curli biogenesis requires 7 curli-specific gene (csg) products-CsgA through G-working in concert.
Manfeng Zhang, Huigang Shi, Xuemei Zhang, Xinzheng Zhang, Yihua Huang   +4 more
doaj   +1 more source

Enhancing the Secretion Systems: Genetic Engineering of Super Bioagents for Effective Plant Disease Control

Biotechnology and Bioengineering, Volume 123, Issue 11, Page 2821-2855, November 2026.
Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
wiley   +1 more source

Beyond Bactericidal: Plasma Surface Engineering to Defeat Food Matrix‐Conditioning Layers

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT The persistence of foodborne pathogens on industrial food contact surfaces continues to challenge global food safety despite advances in sanitation technologies. A central limitation of current antimicrobial strategies lies in their validation under simplified laboratory conditions that overlook the physicochemically driven formation of food ...
Rafael Bianchini Fulindi, Argemiro Soares da Silva Sobrinho, Anderson S. Sant'Ana   +2 more
wiley   +1 more source

Biofilm‐Mediated Persistence of Salmonella in Poultry Processing: A Comprehensive Review of Isolate Heterogeneity, Stress Adaptation, and Antimicrobial Resistance

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Salmonella enterica remains a major foodborne pathogen in poultry‐processing environments, where its persistence is largely attributed to biofilm formation on food‐contact and non‐food‐contact surfaces. Despite extensive research on Salmonella control, persistent contamination continues to challenge food safety due to the complex interplay ...
Md Anamul Hasan Chowdhury, Chowdhury Sanat Anjum Reem, Md Furkanur Rahaman Mizan, Md. Ashrafudoulla, Sang‐Do Ha   +4 more
wiley   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, Volume 13, Issue 57, 14 October 2026.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Congenital curly toe of the fetus [PDF]

Ultrasound in Obstetrics & Gynecology, 2004
AbstractObjectivesTo assess the prevalence, prenatal detection rate, and associated anomalies of congenital curly toe in an unselected obstetric population.MethodsBetween September 2001 and July 2002, 1167 singleton fetuses in the second and third trimesters underwent routine prenatal ultrasound at our hospital.
J Y, Cho, J H, Park, J H, Kim, Y H, Lee
openaire   +2 more sources

Curli fiber production in growing bacterial cultures as measured by Congo Red fluorescence.

, 2022
A shift in emission maximum for Congo Red upon binding to curli fibers in growing PBP8 cultures was used to help confirm fiber formation for two CsgA-VHH fusions. “No curli” refers to a negative control wherein PBP8 was transformed with a plasmid bearing
Xi Qian (1919626), Abhineet Sheoran (13176101), James N. Lee (13803934), Marcia S. Osburne (13803952), Loranne Magoun (13803937), Neel S. Joshi (1632256), Justyna J. Jaskiewicz (13803931), Anishma Shrestha (7042577), Charles B. Shoemaker (189753), Jacqueline M. Tremblay (11914529), Yousuf Aqeel (3738403), Colter Giem (13803940), Xiaoli Li (279663), Saul Tzipori (37482), Avinash Manjula-Basavanna (13803943), John M. Leong (7921661), Ilia Gelfat (9757100), Daniela Bedenice (189740), Hann X. Tu (13803949), Shenglan Hu (5877566), Marilyn L. Minus (2296468), Amanda R. Pulsifer (13803946)   +21 more
core   +1 more source

Attachment and internalization of bioluminescent derivatives of curli and non-curli Escherichia coli O157:H7 to romaine lettuce

, 2009
Escherichia coli O157:H7 is a known causative agent of foodborne illness that is frequently associated with the contamination of fresh produce. The attachment mechanisms used by E.
Tanner, Patti
core   +1 more source

Bacterial amyloid curli activates the host unfolded protein response via IRE1α in the presence of HLA-B27

Gut Microbes
Salmonella enterica serovar Typhimurium (STm) causes gastroenteritis and can progress to reactive arthritis (ReA). STm forms biofilms in the gut that secrete the amyloid curli, which we previously demonstrated can trigger autoimmunity in mice. HLA-B27 is
Kaitlyn Grando, Shingo Bessho, Kayla Harrell, Kathrine Kyrylchuk, Alejandro M. Pantoja, Sophia Olubajo, Francisco J. Albicoro, Andres Klein-Szanto, Çagla Tükel   +8 more
doaj   +1 more source

Mutant and curli-producing E. coli enhance the disease phenotype in a hSOD1-G93A mouse model of ALS

Scientific Reports, 2023
The gut microbiome is a potential non-genetic contributing factor for Amyotrophic Lateral Sclerosis. Differences in gut microbial communities have been detected between ALS subjects and healthy controls, including an increase in Escherichia coli in ALS ...
Zimple Kurlawala, Joseph D. McMillan, Richa A. Singhal, Johnny Morehouse, Darlene A. Burke, Sophia M. Sears, Eleonora Duregon, Levi J. Beverly, Leah J. Siskind, Robert P. Friedland   +9 more
doaj   +1 more source